Kidney Failure Risk Equation predictive tool to improve predialysis patient management?

Abstract

The Kidney Failure Risk Equation (KFRE) is a predictive tool that estimates the risk of progression to end-stage renal disease (ESKD) in patients with chronic kidney disease (CKD). This study evaluated the systematic implementation of KFRE in our nephrology center to improve the management of pre-dialysis patients. Through the analysis of 100 patients followed in the pre-dialysis pathway in the last 36 months, we observed a significant reduction in the initiation of dialysis in late referral mode, a lower use of temporary central venous catheters and an increase in timely preparation of vascular or peritoneal access. The comparison with historical pre-implementation data (2017-2020) highlighted an improvement in clinical organization and patient awareness in the choice of dialysis modality. The KFRE has proven to be a valid tool for risk stratification, optimizing the timing of renal replacement therapy and improving the allocation of healthcare resources. The integration of KFRE into clinical practice could represent a step towards precision nephrology, promoting more informed and personalized therapeutic decisions.