Questionnaire to assess immunosuppressant knowledge among kidney transplant recipients: item generation and content validation

IF 1 Q4 PHARMACOLOGY & PHARMACY

Journal of Pharmacy Practice and Research Pub Date : 2025-02-12 DOI:10.1002/jppr.1973

Nik Aisyah Najwa Nik Mustaffa Shapri MClinPharm, Nurul Syazfeeza Samsudin MClinPharm, Mohd Shahezwan Abd Wahab PhD, Norkasihan Ibrahim PhD

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引用次数: 0

Abstract

Background

Several questionnaires are available to evaluate immunosuppressant knowledge among kidney transplant recipients (KTRs). However, most contain a mixture of questions about different aspects of health management before and after kidney transplantation and do not specifically assess immunosuppressant knowledge.

Aim

This study aimed to generate preliminary items for a questionnaire to assess immunosuppressant knowledge among KTRs, validate the items, and translate the items into Malay.

Method

Preliminary items were generated from domains and subdomains identified through a review of previous questionnaires. Then, the item content was validated in a three-round Delphi study by an expert panel of 11 renal pharmacists. The experts rated the relevance of the items and provided feedback on their comprehensibility and comprehensiveness. Items that attained ≥75% expert agreement on their relevance were considered relevant. Finally, the relevant items were translated into Malay through a forward–backward translation process by three external translators and two researchers. Ethical approval was granted by the Universiti Teknologi MARA Research Ethics Committee (Reference no: REC (PH)PG/027/2022) and the study conforms with the Declaration of Helsinki. Participants were approached electronically, and informed consent was obtained from all participants via distribution of a project information sheet, explaining their participation was voluntary and a gift card would be provided as an incentive upon completion of all three rounds of the Delphi study and completion of a written consent form.

Results

A total of 24 preliminary items were generated. In Round 1 of the Delphi study, four items needed revision, and nine new items were suggested for Round 2 (n = 13). In Round 2, only five of the 13 items were carried forward to Round 3. In the final round, only one of the five items was relevant. The final experts' revision produced 27 items. A Malay-language questionnaire equivalent to the English version was produced.

Conclusion

A content-validated questionnaire consisting of 27 items in English and Malay was produced. This questionnaire serves as a reliable tool to identify immunosuppressant knowledge gaps and evaluate the impacts of educational interventions.

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评估肾移植受者免疫抑制剂知识的问卷：项目生成和内容验证

背景：有几份问卷可以评估肾移植受者（KTRs）的免疫抑制剂知识。然而，大多数包含关于肾移植前后健康管理的不同方面的问题，并且没有具体评估免疫抑制剂知识。目的本研究拟编制一份初步的调查问卷，以评估ktr患者对免疫抑制剂的认知，并对问卷进行验证，并将问卷翻译成马来文。方法通过对先前问卷的回顾，从确定的域和子域生成初步项目。然后，由11名肾脏药师组成的专家小组在三轮德尔菲研究中对项目内容进行验证。专家们对题目的相关性进行了评分，并就题目的可理解性和全面性提供了反馈。相关性达到≥75%专家共识的项目被认为是相关的。最后，由三位外聘译者和两位研究人员通过前后翻译过程将相关条目翻译成马来语。伦理批准由Universiti teknologii MARA研究伦理委员会（参考编号：REC (PH)PG/027/2022）授予，该研究符合赫尔辛基宣言。通过电子方式接触参与者，并通过分发项目信息表获得所有参与者的知情同意，解释他们的参与是自愿的，并在完成所有三轮德尔菲研究并完成书面同意书后，将提供礼品卡作为奖励。结果共生成24个初步项目。在德尔菲研究的第一轮中，有4个项目需要修改，在第二轮中有9个新项目被建议修改（n = 13）。在第二轮比赛中，13项中只有5项被延续到第三轮。在最后一轮中，五个项目中只有一个是相关的。专家最终的修改产生了27个项目。制作了一份相当于英文版本的马来语调查表。结论编制了包含27个题目的马来语和英语问卷。该问卷是确定免疫抑制剂知识差距和评估教育干预影响的可靠工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Pharmacy Practice and Research Health Professions-Pharmacy

CiteScore

1.60

自引率

9.50%

发文量

期刊介绍： The purpose of this document is to describe the structure, function and operations of the Journal of Pharmacy Practice and Research, the official journal of the Society of Hospital Pharmacists of Australia (SHPA). It is owned, published by and copyrighted to SHPA. However, the Journal is to some extent unique within SHPA in that it ‘…has complete editorial freedom in terms of content and is not under the direction of the Society or its Council in such matters…’. This statement, originally based on a Role Statement for the Editor-in-Chief 1993, is also based on the definition of ‘editorial independence’ from the World Association of Medical Editors and adopted by the International Committee of Medical Journal Editors.