Electrical XPS Meets Bio: In-Situ Chemo-Electrical Sensing and Activation of Organic Materials

IF 2.9 3区化学 Q3 CHEMISTRY, PHYSICAL

Physical Chemistry Chemical Physics Pub Date : 2025-07-03 DOI:10.1039/d4cp03762f

Marco Miali, Ulyana Shimanovich, Hagai Cohen

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引用次数: 0

Abstract

X-ray photoelectron spectroscopy (XPS) is a popular analytical technique in material sciences thanks to its versatile coverage of broad energy ranges and the reliability of its quantitative compositional analysis. Hence, tailoring the XPS capabilities into research frontiers of biological systems and nature-inspired materials can potentially become of great value. However, XPS applications to bio/organic systems encounter critical inherent challenges, specifically amplified by the rich nuances that are at the heart of biological functions. The present mini review describes some of these difficulties, showing that by combining electrical-sensing capabilities in-situ to the standard XPS chemical analysis, diverse and effective solutions are proposed. A related method, termed chemically resolved electrical measurements (CREM), is described and case study examples are provided, ranging from self-assembled monolayers of small molecules to relatively large supramolecular sugars and proteins. Detailed discussion is dedicated to specimen stability issues, charge capturing and hot-charge transport functionalities, for which the CREM approach proposes particularly attractive capabilities and a template for advanced characterization strategies.

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电XPS满足生物：原位化学-电传感和有机材料的激活

x射线光电子能谱（XPS）由于其广泛的能量范围和定量成分分析的可靠性，在材料科学中是一种流行的分析技术。因此，将XPS功能应用于生物系统和自然启发材料的研究前沿可能具有巨大的价值。然而，XPS在生物/有机系统中的应用遇到了关键的固有挑战，特别是被生物功能核心的丰富细微差别放大了。本综述描述了其中的一些困难，表明通过将原位电传感能力与标准XPS化学分析相结合，提出了多种有效的解决方案。描述了一种相关的方法，称为化学分辨电测量（CREM），并提供了案例研究示例，范围从小分子的自组装单层到相对较大的超分子糖和蛋白质。详细讨论了样品稳定性问题，电荷捕获和热电荷传输功能，为此CREM方法提出了特别有吸引力的功能和高级表征策略的模板。

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来源期刊

Physical Chemistry Chemical Physics 化学-物理：原子、分子和化学物理

CiteScore

5.50

自引率

9.10%

发文量

2675

审稿时长

2.0 months

期刊介绍： Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.