Informatics at the Frontier of Cancer Research

IF 16.6 1区医学 Q1 ONCOLOGY

Cancer research Pub Date : 2025-07-02 DOI:10.1158/0008-5472.can-24-2829

Kathleen Noller, Taxiarchis Botsis, Pablo G. Camara, Lauren Ciotti, Lee AD. Cooper, Jeremy Goecks, Malachi Griffith, Brian J. Haas, Trey Ideker, Rachel Karchin, Despina Kontos, Jiaying Lai, Daniel Marcus, Clifford A. Meyer, Kristen Naegle, Sarthak Pati, Bjoern Peters, Dexter Pratt, Benjamin J. Raphael, Michael Reich, Guergana K. Savova, Carrie Wright, Elana J. Fertig, Spyridon Bakas

引用次数: 0

Abstract

Digitized healthcare data, high-throughput profiling technologies, and data repositories have facilitated the emergence of a new era of cancer research. Each data stream requires specialized analysis methods for interpretation. The data-driven era of cancer research requires the development, enhancement, and sustainment of informatics technology software infrastructure, including fundamental methodology development in artificial intelligence and data science. We review current and emerging informatics technology developments for cancer research and discovery, spanning molecular and cellular characterization, image analysis, informatics, and therapeutics. Summarizing the diverse methods and applications of informatics throughout cancer research identifies themes and emerging areas for the next generation of cancer research.

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癌症研究前沿的信息学

数字化医疗数据、高通量分析技术和数据存储库促进了癌症研究新时代的出现。每个数据流都需要专门的分析方法来解释。数据驱动的癌症研究时代需要信息技术软件基础设施的发展、增强和维持，包括人工智能和数据科学的基本方法开发。我们回顾了当前和新兴的癌症研究和发现的信息学技术发展，涵盖分子和细胞表征，图像分析，信息学和治疗学。总结不同的方法和信息学在整个癌症研究中的应用，确定下一代癌症研究的主题和新兴领域。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cancer research 医学-肿瘤学

CiteScore

16.10

自引率

0.90%

发文量

7677

审稿时长

2.5 months

期刊介绍： Cancer Research, published by the American Association for Cancer Research (AACR), is a journal that focuses on impactful original studies, reviews, and opinion pieces relevant to the broad cancer research community. Manuscripts that present conceptual or technological advances leading to insights into cancer biology are particularly sought after. The journal also places emphasis on convergence science, which involves bridging multiple distinct areas of cancer research. With primary subsections including Cancer Biology, Cancer Immunology, Cancer Metabolism and Molecular Mechanisms, Translational Cancer Biology, Cancer Landscapes, and Convergence Science, Cancer Research has a comprehensive scope. It is published twice a month and has one volume per year, with a print ISSN of 0008-5472 and an online ISSN of 1538-7445. Cancer Research is abstracted and/or indexed in various databases and platforms, including BIOSIS Previews (R) Database, MEDLINE, Current Contents/Life Sciences, Current Contents/Clinical Medicine, Science Citation Index, Scopus, and Web of Science.