A ten-year retrospective California Poison Control System experience with water bead exposures: a growing problem.

IF 3.3
Justin C Lewis, Jacqueline C Stocking, Maheen Hassan, Timothy E Albertson, Minna M Wieck
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Abstract

Introduction: Water beads are superabsorbent children's toys that expand in water. When ingested, they can cause intestinal obstruction. Beyond case reports of ingestion-related morbidity, healthcare utilization and management have not been well-described. This study evaluates the experience of a large poison system with water bead exposures.

Methods: A 10-year retrospective review (2014-2023) of the California Poison Control System database was performed. Water bead exposures were identified using product codes and a keyword free-text search for "Orbeez" and "water bead." Demographic and clinical data were abstracted and statistically analyzed for association with a composite endpoint of imaging, endoscopy, surgery and/or need for hospital admission, which was a surrogate measure for clinical acuity.

Results: There were 2,280 water bead exposures. The number increased from 23 patients in 2014 to 1,257 cases in 2023. Thirty-seven (8.1%) patients reached the composite endpoint. Imaging was at the discretion of the treating provider and included radiographs (35 patients), ultrasound examinations (two patients), and computed tomography scan (two patients). One patient underwent endoscopy. No patients required surgery, and no deaths occurred. Patients with symptoms after exposure had 77% increased odds of reaching the composite outcome. Statistically significant symptoms included abdominal pain, nausea/vomiting, constipation, diarrhea, abdominal distention, and fever. Behavioral issues, which included autism and psychiatric diagnoses, were significantly (P = 0.020) associated with reaching the composite outcome.

Discussion: The number of water bead exposures reported to Californian poison centers has increased over the past 10 years despite regulatory and prevention efforts. Few water bead exposures in our series resulted in procedures, surgeries, or hospitalizations over the study period. More evaluations were performed for children who presented with symptoms.

Conclusion: Even if few cases required procedural intervention, substantial resources were used to address water bead exposures. More stringent regulations, widespread public awareness, and proactive education are needed to curb this potentially dangerous trend.

十年回顾加州中毒控制系统的经验与水珠暴露:一个日益严重的问题。
导读:水珠是一种在水中膨胀的高吸水性儿童玩具。当摄入时,它们会引起肠梗阻。除了病例报告摄入相关的发病率,医疗保健的利用和管理没有很好的描述。本研究评估了与水珠接触的大型中毒系统的经验。方法:对加州毒物控制系统数据库(2014-2023)进行10年回顾性分析。水珠暴露是通过产品代码和关键词自由文本搜索“Orbeez”和“水珠”来识别的。提取人口统计学和临床数据,并对其与影像学、内窥镜检查、手术和/或住院需求等复合终点的关联进行统计分析,后者是临床视力的替代指标。结果:水珠暴露2280例。从2014年的23例增加到2023年的1257例。37例(8.1%)患者达到了复合终点。影像学检查由治疗提供者决定,包括x线片(35例患者)、超声检查(2例患者)和计算机断层扫描(2例患者)。一名患者接受了内窥镜检查。没有病人需要手术,也没有人死亡。暴露后出现症状的患者达到复合结果的几率增加了77%。有统计学意义的症状包括腹痛、恶心/呕吐、便秘、腹泻、腹胀和发烧。行为问题,包括自闭症和精神诊断,与达到综合结果显著相关(P = 0.020)。讨论:在过去的10年里,尽管有监管和预防措施,但向加州中毒中心报告的水珠暴露数量仍在增加。在我们的研究中,很少有水珠暴露导致治疗、手术或住院治疗。对出现症状的儿童进行了更多的评估。结论:即使少数病例需要程序性干预,大量的资源用于解决水珠暴露。为了遏制这种潜在的危险趋势,需要更严格的法规、广泛的公众意识和积极的教育。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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