A 5-year retrospective outlook of cardiovascular risk(s), outcome and survival peculiarities among patients in medical confinement; a tropical perspective.

Titilope A Bamikefa, Peter K Uduagbamen, Olanrewaju O Olayemi, Olufemi O Ojewuyi, Oyelola Adeoye, Sekinat Bola-Oyebamiji, Olubukola Ala, Abosede G Adeyeye
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Abstract

Objective: The study was designed to evaluate the distribution of cardiovascular risk(s), outcome modifiers and survival peculiarities among medically confined patients.

Design: Evaluated admission and discharge summaries of medically confined patients retroactively over 5 years.

Setting: Medical wards, UniOsun Teaching Hospital Osogbo, Osun State, Nigeria.

Participants: Two thousand three hundred and forty (2340) male and female patients aged between 16 and 108 years.

Main outcome measures: Admission pattern, cardiovascular risk distribution, outcome and survival peculiarities.

Results: The mean age of the respondents was 53.2 (18.3) years with male preponderance (52.0%). Non-infectious diseases predominated as the principal causes of medical confinements (82.9%). Cerebrovascular accident (13.5%), acute decompensation of chronic kidney disease (11.6%) and type 2 diabetes mellitus (6.0%) were the prominent causes of morbidity. The median duration of confinement was 6.0 days. The overall crude mortality rate was 14.3%, with the highest case fatality rate (27.2%) among those with neurological morbidities. Clinical outcome was statistically influenced by age (p= 0.004), occupation (p=0.02), duration of confinement (p=0.002) and morbidity stratification into infectious/non-infectious aetiologies (p=0.040) on regression analysis. The number of medical sub-specialties involved (p < 0.001), specialty affected (p<0.001), and yearly pattern of hospitalisation (p< 0.001) had a statistical influence on Kaplan Meier's survival plots.

Conclusion: Hospital confinements underlined by infection/non-infection-related medical causes exhibit variable outcomes. The loop-sided frequencies of its causes remain worrisome because of the unending challenges plaguing effective healthcare delivery in the tropics.

Funding: None declared.

Abstract Image

Abstract Image

医学隔离患者心血管风险、预后和生存特点的5年回顾性研究热带视角。
目的:本研究旨在评估医学限制患者的心血管风险分布、结局改变因素和生存特点。设计:回顾性评估5年以上医学限制患者的入院和出院总结。地点:尼日利亚奥松州奥索博联盛教学医院病房。参与者:2340名年龄在16岁至108岁之间的男性和女性患者。主要结局指标:入院模式、心血管风险分布、结局和生存特点。结果:调查对象平均年龄53.2岁(18.3岁),男性占52.0%;非传染性疾病是住院的主要原因(82.9%)。脑血管意外(13.5%)、慢性肾脏疾病急性失代偿(11.6%)和2型糖尿病(6.0%)是发病的主要原因。坐月子的中位持续时间为6.0天。总粗死亡率为14.3%,其中神经系统疾病的病死率最高(27.2%)。年龄(p= 0.004)、职业(p=0.02)、禁闭时间(p=0.002)和感染/非感染病因分层(p=0.040)对临床结果有统计学影响。结论:以感染/非感染相关医学原因为重点的住院住院表现出不同的结局。其原因的循环频率仍然令人担忧,因为在热带地区,有效的医疗保健服务面临着无休止的挑战。资金:未宣布。
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