Cheng Li , Kai Wang , Haitao Gan , Ran Zhou , Xinyao Cheng , Zhi Yang
{"title":"FeaCL: Carotid plaque classification from ultrasound images using feature-level and instance-level contrast learning","authors":"Cheng Li , Kai Wang , Haitao Gan , Ran Zhou , Xinyao Cheng , Zhi Yang","doi":"10.1016/j.compmedimag.2025.102590","DOIUrl":null,"url":null,"abstract":"<div><div>The classification of carotid plaques from ultrasound images in clinical application is crucial for predicting patient risks of cardiovascular and cerebrovascular diseases, as well as for developing appropriate treatment strategies. Although the effectiveness of deep learning in this domain is well-established, its performance is often limited by the scarcity of labeled carotid plaque images. To address label scarcity, we present a novel self-supervised learning technique known as FEature-level and instAnce-level contrast learning (FeaCL) to enhance carotid plaque classification. FeaCL first utilizes a triplet network in the pretext task where the strong- and weak-augmentation approach is employed. The triplet network promotes the similarity of the three different views from both feature and instance perspectives to learn effective representation of carotid plaques. Then in the downstream task, the encoder network is initialized by the network trained in the pretext task, and updated using labeled ultrasound images. Experimental results on an ultrasound image dataset show that FeaCL achieved a classification accuracy of 83.4% with 30% of the training data, marking an improvement of 16.3% compared to the network without the pretext task. It is indicated that FeaCL can help clinicians diagnose the type of carotid plaque and evaluate the risk of the disease. The source code is available at: <span><span>https://github.com/a610lab/FeaCL</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":50631,"journal":{"name":"Computerized Medical Imaging and Graphics","volume":"124 ","pages":"Article 102590"},"PeriodicalIF":4.9000,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computerized Medical Imaging and Graphics","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0895611125000990","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
The classification of carotid plaques from ultrasound images in clinical application is crucial for predicting patient risks of cardiovascular and cerebrovascular diseases, as well as for developing appropriate treatment strategies. Although the effectiveness of deep learning in this domain is well-established, its performance is often limited by the scarcity of labeled carotid plaque images. To address label scarcity, we present a novel self-supervised learning technique known as FEature-level and instAnce-level contrast learning (FeaCL) to enhance carotid plaque classification. FeaCL first utilizes a triplet network in the pretext task where the strong- and weak-augmentation approach is employed. The triplet network promotes the similarity of the three different views from both feature and instance perspectives to learn effective representation of carotid plaques. Then in the downstream task, the encoder network is initialized by the network trained in the pretext task, and updated using labeled ultrasound images. Experimental results on an ultrasound image dataset show that FeaCL achieved a classification accuracy of 83.4% with 30% of the training data, marking an improvement of 16.3% compared to the network without the pretext task. It is indicated that FeaCL can help clinicians diagnose the type of carotid plaque and evaluate the risk of the disease. The source code is available at: https://github.com/a610lab/FeaCL.
期刊介绍:
The purpose of the journal Computerized Medical Imaging and Graphics is to act as a source for the exchange of research results concerning algorithmic advances, development, and application of digital imaging in disease detection, diagnosis, intervention, prevention, precision medicine, and population health. Included in the journal will be articles on novel computerized imaging or visualization techniques, including artificial intelligence and machine learning, augmented reality for surgical planning and guidance, big biomedical data visualization, computer-aided diagnosis, computerized-robotic surgery, image-guided therapy, imaging scanning and reconstruction, mobile and tele-imaging, radiomics, and imaging integration and modeling with other information relevant to digital health. The types of biomedical imaging include: magnetic resonance, computed tomography, ultrasound, nuclear medicine, X-ray, microwave, optical and multi-photon microscopy, video and sensory imaging, and the convergence of biomedical images with other non-imaging datasets.