Is membership in microfinance initiatives associated with viral load suppression among HIV patients? Evidence from western Kenya.

Bishnu Bahadur Thapa, Becky Genberg, Juddy Wachira, Jon Steingrimsson, Omar Galarraga
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Abstract

Background: Social and economic factors have considerable influence on the lives of people living with HIV (PLHIV). These factors shape their health behaviors, willingness to engage with other members of their communities for support, and ability to seek appropriate and timely treatment options. Evidence has shown that microfinance initiatives, by providing access to credit and social networks, have the potential to help PLHIV overcome some of these barriers. The objective of this study was to understand the association between microfinance membership and viral load suppression among HIV patients.

Methods: We used data from the Academic Model Providing Access to Healthcare (AMPATH)-Kenya's Group Integrated Savings for Health Empowerment (GISHE), a microfinance initiative (MFI), to study the association between GISHE participation and viral load suppression. Our longitudinal dataset consisted of a matched group of 3609 HIV patients. We examined the association between GISHE membership and viral load suppression by addressing the missing data problem with respect to the viral load count via multiple imputation.

Results: Our study revealed that GISHE membership was associated with increased viral load suppression (adjusted odds ratio (AOR) = 1.15; 95% confidence interval (CI), 1.03-1.29). Further, the study found that male patients were less likely to be virally suppressed (AOR = 0.85; 95% CI, 0.74-0.97), as were the patients in the most advanced disease stage (AOR = 0.71; 95% CI, 0.52-0.95). The finding that GISHE participation was associated with a greater likelihood of viral load suppression held even after addressing the missing data problem.

Conclusions: We conclude that GISHE-type programs hold promise as scalable interventions to combat HIV/AIDS in Kenya and other countries where the disease is a generalized epidemic.

小额信贷计划的成员资格是否与HIV患者的病毒载量抑制有关?证据来自肯尼亚西部。
背景:社会和经济因素对艾滋病毒感染者(PLHIV)的生活有相当大的影响。这些因素决定了他们的健康行为、与社区其他成员接触以获得支持的意愿以及寻求适当和及时治疗方案的能力。有证据表明,小额信贷倡议通过提供获得信贷和社交网络的途径,有可能帮助艾滋病毒感染者克服其中一些障碍。本研究的目的是了解小额信贷会员和HIV患者病毒载量抑制之间的关系。方法:我们使用来自提供医疗保健的学术模型(AMPATH)-肯尼亚的群体健康赋权综合储蓄(GISHE),一项小额信贷倡议(MFI)的数据,研究GISHE参与与病毒载量抑制之间的关系。我们的纵向数据集由3609名HIV患者组成。我们通过多次代入解决关于病毒载量计数的数据缺失问题,研究了GISHE成员资格与病毒载量抑制之间的关系。结果:我们的研究显示GISHE成员与病毒载量抑制增加相关(调整优势比(AOR) = 1.15;95%置信区间(CI), 1.03-1.29)。此外,研究发现男性患者更不可能被病毒抑制(AOR = 0.85;95% CI, 0.74-0.97),疾病晚期患者也是如此(AOR = 0.71;95% ci, 0.52-0.95)。即使在解决了缺失数据问题之后,GISHE参与与病毒载量抑制的更大可能性相关的发现仍然成立。结论:我们的结论是,gishe类型的项目有望作为可扩展的干预措施,在肯尼亚和其他疾病普遍流行的国家对抗艾滋病毒/艾滋病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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