A Literature Review of the Lubricants Used in Dermatome-Assisted Split-Thickness Skin Graft Harvest.

IF 2.9 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
William Wright, Marc Ingram, Quentin Frew
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Abstract

Background: Split-thickness skin grafts (STSGs) are utilised to close wounds which cannot be closed by primary closure. Dermatome-assisted STSG harvest utilises a lubricant to control friction, which facilitates graft harvest. Many different lubricants are used during graft harvest, although little research has been conducted to identify the optimal lubricant. Furthermore, new techniques such as Meek grafting are incompatible with commonly used oil-based lubricants. Method: A literature search was conducted, following the PRISMA protocol. 173 records were screened with 6 included in this study. We also reviewed the literature on lubricants in other biotribological systems including shaving. Results: We found support for numerous lubricants, including: mineral oil, catheter gel, chlorhexidine, saline and ultrasound gel. Evidence consisted of expert opinions, and one blinded comparative review. There was no consensus on the optimal lubricant, and we did not find evidence that lubricant compatibility with Meek grafting had been assessed. Conclusions: Presently, lubrication choice in STSG harvest lacks a scientific basis, and further research is needed to design a bespoke, Meek-compatible lubricant which considers only four of Engelhardt's characteristics (1. cost-effectiveness; 4. lubrication; 6. no side effects; 8. practicability) to be essential. This should be followed by a blinded trial of lubricants.

皮体辅助剥厚皮肤移植术中所用润滑剂的文献综述。
背景:裂厚皮肤移植物(STSGs)用于缝合不能通过初次缝合的伤口。皮肤组织辅助的STSG收获利用润滑剂来控制摩擦,从而促进移植物收获。在嫁接收获过程中使用了许多不同的润滑剂,尽管很少有研究来确定最佳润滑剂。此外,Meek接枝等新技术与常用的油基润滑剂不相容。方法:采用文献检索,按照PRISMA规程进行。共筛选173份病历,其中6份纳入本研究。我们也回顾了润滑油在其他生物摩擦学系统中的应用,包括剃须。结果:我们发现支持多种润滑剂,包括:矿物油,导管凝胶,氯己定,生理盐水和超声凝胶。证据包括专家意见和一项盲法比较评价。在最佳润滑剂方面没有达成共识,我们也没有发现证据表明润滑剂与Meek嫁接的相容性已经被评估过。结论:目前,STSG收获中的润滑选择缺乏科学依据,需要进一步研究设计一种定制的、meek兼容的润滑油,该润滑油只考虑Engelhardt的四个特性(1)。成本效益;4. 润滑;6. 无副作用;8. 实用性)是必不可少的。接下来应该进行润滑油的盲法试验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Clinical Medicine
Journal of Clinical Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
5.70
自引率
7.70%
发文量
6468
审稿时长
16.32 days
期刊介绍: Journal of Clinical Medicine (ISSN 2077-0383), is an international scientific open access journal, providing a platform for advances in health care/clinical practices, the study of direct observation of patients and general medical research. This multi-disciplinary journal is aimed at a wide audience of medical researchers and healthcare professionals. Unique features of this journal: manuscripts regarding original research and ideas will be particularly welcomed.JCM also accepts reviews, communications, and short notes. There is no limit to publication length: our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible.
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