Tubal Ectopic Pregnancy: From Diagnosis to Treatment.

IF 3.9 3区 工程技术 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Dimitrios Papageorgiou, Ioakeim Sapantzoglou, Ioannis Prokopakis, Eleftherios Zachariou
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Abstract

The most frequent form of ectopic pregnancy, known as tubal pregnancy, leads to a dangerous situation where the fertilized ovum implants inside a fallopian tube, which can result in tubal rupture and severe bleeding. The purpose of this narrative review is to evaluate all existing data regarding epidemiology, risk factors, pathophysiology, clinical presentation, diagnosis, and management of tubal ectopic pregnancy in order to provide a comprehensive understanding of this common yet difficult clinical condition. Prior ectopic pregnancy, together with tubal pathology and assisted reproduction, represent the main risk factors for this condition. The diagnosis relies on serial β-hCG tests combined with transvaginal ultrasonography, but laparoscopy serves as the diagnostic tool for cases with uncertain results. The treatment plan depends on the fallopian tube integrity, along with the patient's hemodynamic condition. Patients with unruptured pregnancies who are hemodynamically stable receive methotrexate treatment as the preferred option, but surgical intervention with salpingectomy or salpingostomy becomes necessary in case of tubal rupture or when medical treatment fails. The development of laparoscopic procedures has led to better results and improved possibilities for fertility preservation. The psychological effects on patients require both counseling and follow-up care. Early detection, along with personalized management, helps decrease maternal complications and optimize reproductive outcomes.

输卵管异位妊娠:从诊断到治疗。
宫外孕最常见的形式,被称为输卵管妊娠,会导致受精卵植入输卵管内的危险情况,这可能导致输卵管破裂和严重出血。这篇叙述性综述的目的是评估所有现有的关于输卵管异位妊娠的流行病学、危险因素、病理生理学、临床表现、诊断和治疗的资料,以便对这种常见但困难的临床情况有一个全面的了解。先前的异位妊娠,连同输卵管病理和辅助生殖,是这种情况的主要危险因素。诊断依赖于一系列β-hCG检查结合阴道超声检查,但对于结果不确定的病例,腹腔镜检查可作为诊断工具。治疗方案取决于输卵管的完整性,以及患者的血流动力学状况。未破裂妊娠且血流动力学稳定的患者首选甲氨蝶呤治疗,但在输卵管破裂或药物治疗失败的情况下,手术干预输卵管切除术或输卵管造口术是必要的。腹腔镜手术的发展带来了更好的结果,并提高了保留生育能力的可能性。对患者的心理影响需要咨询和后续护理。早期发现和个性化管理有助于减少产妇并发症和优化生殖结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomedicines
Biomedicines Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology
CiteScore
5.20
自引率
8.50%
发文量
2823
审稿时长
8 weeks
期刊介绍: Biomedicines (ISSN 2227-9059; CODEN: BIOMID) is an international, scientific, open access journal on biomedicines published quarterly online by MDPI.
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