Multicenter Study of Comorbidities in Patients with Periprosthetic Fractures After Total Hip Arthroplasty and Their Association with Immediate Postoperative Complications.

IF 1.7 Q2 MEDICINE, GENERAL & INTERNAL
Victor Niculescu, Alexandru Lisias Dimitriu, Delia Carmen Nistor-Cseppento, Sebastian Tirla, Anamaria Gherle, Bogdan Uivaraseanu, Cristian Burnei
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Abstract

Background/Objectives: Periprosthetic fractures (PFs) can occur in both the upper and lower limbs, commonly resulting from falls at the same level. The frequency of PFs following total hip arthroplasty (THA) ranges from 0.045% to 4.1%, and this incidence is influenced by several factors, including age, gender, the type of prosthesis used, and existing comorbidities. Previous studies on this subject have been small in scale and did not adequately address the associated comorbidities, which pose a challenge for the aging population. This study aims to comparatively assess the incidence of THA-related PFs, immediate postoperative complications, and comorbidities in patients with PFs from three emergency hospitals. Methods: A retrospective observational study was conducted from 1 January to 31 December 2024, in which 54 patients with PFs hospitalized in three emergency hospitals (Bucharest, Oradea, and Ploiești) were evaluated, divided into Group B (n = 29), Group O (n = 14), and Group P (n = 11). Results: Of all patients with PFs, 81.48% had minor complications-grade 1, 9.26% had grade 2 complications (complications requiring medical treatment or other minor interventions), and 3.70% had complications requiring surgery or invasive procedures. Clavien-Dindo grade 5 (patient death) had an incidence of 3.70%. Cardiac pathology was the most common pathology; hypertension predominated in Group O (42.85%). Alzheimer's disease was associated in 7 patients (12.96%). Without associated pathology, about 13% of patients were identified. Diabetes mellitus also occurred frequently in 31.50%. Data analysis indicates a very weak positive correlation between the Dindo Index and the Charlson Comorbidity Index (r = 0.046), which is not statistically significant (p = 0.628). The effect size, measured by Fisher's z, is also reported as 0.046. Conclusions: No significant differences were found among the evaluated centers regarding therapeutic approaches, postoperative complications, and associated comorbidities. Furthermore, there is insufficient evidence to suggest a significant association between the Charlson Comorbidity Index and the Clavien-Dindo Index.

全髋关节置换术后假体周围骨折患者合并症及其与术后即刻并发症的关系的多中心研究
背景/目的:假体周围骨折(PFs)可发生在上肢和下肢,通常由同一水平的跌倒引起。全髋关节置换术(THA)后发生PFs的频率从0.045%到4.1%不等,这一发生率受几个因素的影响,包括年龄、性别、使用的假体类型和现有的合并症。以往关于该主题的研究规模较小,并没有充分解决相关的合并症,这对人口老龄化构成了挑战。本研究旨在比较评估三家急诊医院的前列腺癌相关PFs患者的发生率、术后即刻并发症和合并症。方法:对2024年1月1日至12月31日在布加勒斯特、奥拉迪亚和Ploiești三家急诊医院住院的54例PFs患者进行回顾性观察,分为B组(n = 29)、O组(n = 14)和P组(n = 11)。结果:在所有PFs患者中,81.48%的患者有1级轻微并发症,9.26%的患者有2级并发症(需要药物治疗或其他轻微干预的并发症),3.70%的患者有需要手术或侵入性手术的并发症。Clavien-Dindo 5级(患者死亡)发生率为3.70%。心脏病理是最常见的病理;O组以高血压为主(42.85%)。伴有阿尔茨海默病7例(12.96%)。没有相关病理,约13%的患者被确诊。糖尿病发生率为31.50%。数据分析显示Dindo指数与Charlson共病指数呈极弱正相关(r = 0.046),无统计学意义(p = 0.628)。用费雪z衡量的效应大小也被报道为0.046。结论:在评估的中心中,在治疗方法、术后并发症和相关合并症方面没有发现显著差异。此外,没有足够的证据表明查理森合并症指数和Clavien-Dindo指数之间有显著的关联。
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来源期刊
Clinics and Practice
Clinics and Practice MEDICINE, GENERAL & INTERNAL-
CiteScore
2.60
自引率
4.30%
发文量
91
审稿时长
10 weeks
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