A review of bidentate NN and NO Schiff base ligands and metal complexes

IF 2.7 3区化学 Q2 CHEMISTRY, INORGANIC & NUCLEAR

Inorganica Chimica Acta Pub Date : 2025-06-17 DOI:10.1016/j.ica.2025.122822

Mehdi Fallah-Mehrjardi , Hadi Kargar , Muhammad Ashfaq , Khurram Shahzad Munawar

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引用次数: 0

Abstract

The article reviews our studies on the synthesis, structural elucidation, spectral properties, and applications of bidentate NN and NO Schiff base ligands and their corresponding metal complexes. Upon coordination, Schiff base complexes with distinct geometries like tetrahedral, square planar, or distorted trigonal planar were synthesized as confirmed by SC-XRD and spectroscopic techniques (FT-IR, NMR). Some polymeric copper (I) complexes exhibit exceptional catalytic efficiency in the synthesis of N-heterocycles (e.g., tetrahydropyrimidines and 1,2,3-triazoles), achieving high yields under mild conditions. The chelated Schiff base ligands display superior bacteriostatic effects against both Gram-positive (S. aureus) and Gram-negative (E. coli) pathogens compared to non-coordinated ligands, as quantified through standardized MIC/MBC assays. Overall, this review highlights the versatility of Schiff base metal complexes in antimicrobial applications and catalysis, emphasizing their structural tunability and functional potential in coordination chemistry.

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双齿NN和NO席夫碱配体和金属配合物的研究进展

本文综述了双齿NN和NO席夫碱配体及其金属配合物的合成、结构解析、光谱性质及应用等方面的研究进展。配位后，经SC-XRD和光谱技术（FT-IR、NMR）证实，合成了具有不同几何形状的席夫碱配合物，如四面体、方形平面或畸变三角平面。一些聚合铜(I)配合物在合成n -杂环（如四氢嘧啶和1,2,3-三唑）中表现出特殊的催化效率，在温和的条件下获得了高收率。通过标准化MIC/MBC测定，与非配位配体相比，螯合的希夫碱配体对革兰氏阳性（金黄色葡萄球菌）和革兰氏阴性（大肠杆菌）病原体均显示出更好的抑菌效果。总之，本文综述了希夫碱金属配合物在抗菌和催化方面的多功能性，强调了它们在配位化学中的结构可调性和功能潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Inorganica Chimica Acta 化学-无机化学与核化学

CiteScore

6.00

自引率

3.60%

发文量

440

审稿时长

35 days

期刊介绍： Inorganica Chimica Acta is an established international forum for all aspects of advanced Inorganic Chemistry. Original papers of high scientific level and interest are published in the form of Articles and Reviews. Topics covered include: • chemistry of the main group elements and the d- and f-block metals, including the synthesis, characterization and reactivity of coordination, organometallic, biomimetic, supramolecular coordination compounds, including associated computational studies; • synthesis, physico-chemical properties, applications of molecule-based nano-scaled clusters and nanomaterials designed using the principles of coordination chemistry, as well as coordination polymers (CPs), metal-organic frameworks (MOFs), metal-organic polyhedra (MPOs); • reaction mechanisms and physico-chemical investigations computational studies of metalloenzymes and their models; • applications of inorganic compounds, metallodrugs and molecule-based materials. Papers composed primarily of structural reports will typically not be considered for publication.