[S3 guideline on renal replacement therapy in intensive care medicine : Evidence-based implementation of renal replacement therapy in critically ill patients].

IF 1.3 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Medizinische Klinik-Intensivmedizin Und Notfallmedizin Pub Date : 2025-06-23 DOI:10.1007/s00063-025-01293-6

Carsten Willam, Mariam Abu-Tair, Matthias Bayer, Romuald Bellmann, Frank Brunkhorst, Florian Custodis, Jan Galle, Carsten Hermes, Michael Joannidis, Stefan John, Achim Jörres, Thomas Kerz, Detlef Kindgen-Milles, Martin Koczor, Rainer Kram, Martin K Kuhlmann, Michael Oppert, Georg Schlieper, Michael Schmitz, Alexander Zarbock, Melanie Meersch

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Abstract

Besides mechanical ventilation, renal replacement therapy is the most frequently performed organ replacement therapy in intensive care medicine. However, there is a lack of consensus- and evidence-based recommendations for the implementation of renal replacement therapy according to the best current knowledge and evidence. This guideline describes the topics of starting a renal replacement therapy, modality (diffusion or convection, continuous or intermittent procedures), anticoagulation, adequate dose, and criteria for stopping renal replacement therapy. In addition, the current evidence on adequate anti-infective therapy is presented under the special features of acute kidney injury and renal replacement therapy.

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[S3重症医学肾替代治疗指南：危重患者肾替代治疗的循证实施]。

除机械通气外，肾脏替代疗法是重症监护医学中最常用的器官替代疗法。然而，根据目前最好的知识和证据，对实施肾脏替代疗法缺乏共识和循证建议。本指南描述了开始肾脏替代治疗的主题、方式（扩散或对流、连续或间歇治疗）、抗凝、适当剂量和停止肾脏替代治疗的标准。此外，在急性肾损伤和肾替代治疗的特殊特点下，目前关于充分抗感染治疗的证据也被提出。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medizinische Klinik-Intensivmedizin Und Notfallmedizin MEDICINE, GENERAL & INTERNAL-

CiteScore

2.60

自引率

9.10%

发文量

审稿时长

6-12 weeks

期刊介绍： Medizinische Klinik – Intensivmedizin und Notfallmedizin is an internationally respected interdisciplinary journal. It is intended for physicians, nurses, respiratory and physical therapists active in intensive care and accident/emergency units, but also for internists, anesthesiologists, surgeons, neurologists, and pediatricians with special interest in intensive care medicine. Comprehensive reviews describe the most recent advances in the field of internal medicine with special focus on intensive care problems. Freely submitted original articles present important studies in this discipline and promote scientific exchange, while articles in the category Photo essay feature interesting cases and aim at optimizing diagnostic and therapeutic strategies. In the rubric journal club well-respected experts comment on outstanding international publications. Review articles under the rubric "Continuing Medical Education" present verified results of scientific research and their integration into daily practice. The rubrics "Nursing practice" and "Physical therapy" round out the information.