AI-Assisted 3D Planning of CT Parameters for Personalized Femoral Prosthesis Selection in Total Hip Arthroplasty.

IF 2.8 3区 医学 Q1 Pharmacology, Toxicology and Pharmaceutics
Therapeutics and Clinical Risk Management Pub Date : 2025-06-18 eCollection Date: 2025-01-01 DOI:10.2147/TCRM.S521755
Tian-Jiao Yang, Wei Qian
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引用次数: 0

Abstract

Objective: To investigate the efficacy of CT measurement parameters combined with AI-assisted 3D planning for personalized femoral prosthesis selection in total hip arthroplasty (THA).

Methods: A retrospective analysis was conducted on clinical data from 247 patients with unilateral hip or knee joint disorders treated at Renmin Hospital of Hubei University of Medicine between April 2021 and February 2024. All patients underwent preoperative full-pelvis and bilateral full-length femoral CT scans. The raw CT data were imported into Mimics 19.0 software to reconstruct a three-dimensional (3D) model of the healthy femur. Using 3-matic Research 11.0 software, the femoral head rotation center was located, and parameters including femoral head diameter (FHD), femoral neck length (FNL), femoral neck-shaft angle (FNSA), femoral offset (FO), femoral neck anteversion angle (FNAA), tip-apex distance (TAD), and tip-apex angle (TAA) were measured. AI-assisted THA 3D planning system AIJOINT V1.0.0.0 software was used for preoperative planning and design, enabling personalized selection of femoral prostheses with varying neck-shaft angles and surgical simulation. Groups were compared by gender, age, and parameters. ROC curves evaluated prediction efficacy.

Results: Females exhibited smaller FHD, FNL, FO, TAD, TAA but larger FNSA/FNAA vs males (P<0.05). Patients >65 years had higher FO, TAD, TAA (P<0.05). TAD-TAA correlation was strong (r=0.954), while FNSA negatively correlated with TAD/TAA (r=-0.773/-0.701). ROC analysis demonstrated high predictive accuracy: TAD (AUC=0.891, sensitivity=91.7%, specificity=87.6%) and TAA (AUC=0.882, sensitivity=100%, specificity=88.8%).

Conclusion: CT parameters (TAA, TAD, FNSA, FO) are interrelated and effective predictors for femoral prosthesis selection. Integration with AI-assisted planning optimizes personalized THA, reducing biomechanical mismatch risks.

人工智能辅助下全髋关节置换术中股骨假体个性化选择的CT参数三维规划
目的:探讨CT测量参数结合人工智能辅助三维规划在全髋关节置换术(THA)个体化股骨假体选择中的效果。方法:回顾性分析2021年4月至2024年2月在湖北医科大学人民医院治疗的247例单侧髋关节或膝关节疾病患者的临床资料。所有患者术前均行全骨盆和双侧全股骨CT扫描。将原始CT数据导入Mimics 19.0软件,重建健康股骨的三维(3D)模型。采用3-matic Research 11.0软件定位股骨头旋转中心,测量股骨头直径(FHD)、股骨头颈长(FNL)、股骨头颈轴角(FNSA)、股骨偏置(FO)、股骨头颈前倾角(FNAA)、股骨头尖端距离(TAD)、股骨头尖端角(TAA)等参数。采用ai辅助THA三维规划系统AIJOINT V1.0.0.0软件进行术前规划设计,实现不同颈轴角度股骨假体的个性化选择和手术模拟。各组按性别、年龄和参数进行比较。ROC曲线评价预测效果。结果:与男性相比,女性FHD、FNL、FO、TAD、TAA较小,但FNSA/FNAA较大(P65岁患者FO、TAD、TAA较高)。结论:CT参数(TAA、TAD、FNSA、FO)是股骨假体选择的相关有效预测指标。与人工智能辅助规划的集成优化了个性化THA,降低了生物力学失配风险。
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来源期刊
Therapeutics and Clinical Risk Management
Therapeutics and Clinical Risk Management HEALTH CARE SCIENCES & SERVICES-
CiteScore
5.30
自引率
3.60%
发文量
139
审稿时长
16 weeks
期刊介绍: Therapeutics and Clinical Risk Management is an international, peer-reviewed journal of clinical therapeutics and risk management, focusing on concise rapid reporting of clinical studies in all therapeutic areas, outcomes, safety, and programs for the effective, safe, and sustained use of medicines, therapeutic and surgical interventions in all clinical areas. The journal welcomes submissions covering original research, clinical and epidemiological studies, reviews, guidelines, expert opinion and commentary. The journal will consider case reports but only if they make a valuable and original contribution to the literature. As of 18th March 2019, Therapeutics and Clinical Risk Management will no longer consider meta-analyses for publication. The journal does not accept study protocols, animal-based or cell line-based studies.
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