[Polysaccharide composition of the cell wall of Streptomyces antibioticus RIA-594(39), a producer of the antibiotic oleandomycin].

Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology Pub Date : 1987-07-01

M Sh Zaretskaia, A N Polin

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Abstract

The main polysaccharide components of the cell wall in S. antibioticus RIA-594 (39) i.e. peptidoglycan, teichoic acid and polysaccharide were studied. Peptidoglycan consists of the polysaccharide fraction containing equimolar quantities of N-acetylglucosamine and muramic acid and the peptide subunits including alanine, glutamic and L,L-diaminopimelic acids and glycine at a ratio of 1.4:0.9:1:0.9. It is characteristic that certain peptide subunits of the streptomycete contain no alanine. A polysaccharide differing from glycerol teichoic acid and containing galactose and N-acetylglucosamine was isolated from the cell wall. During the streptomycete development the quantity of peptidoglycan remained constant, the quantity of teichoic acid lowered and the quantity of polysaccharide increased. Correlation between the presence of aminosugars in the composition of teichoic acid and polysaccharide specific of the streptomycete cell wall and the presence of aminosugars in the structure of oleandomycin was shown. This is probably connected with characteristic features of the organism physiology.

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[链霉菌抗生素RIA-594细胞壁的多糖组成(39)，抗生素夹竹桃霉素的生产者]。

对抗生素链球菌RIA-594(39)细胞壁的主要多糖成分肽聚糖、壁藻酸和多糖进行了研究。肽聚糖由含有等摩尔量的n -乙酰氨基葡萄糖和谷氨酸的多糖部分和丙氨酸、谷氨酸、L-二氨基亚酸和甘氨酸组成，比例为1.4:0.9:1:9 .9。链霉菌的某些肽亚基不含丙氨酸是其特征。从细胞壁中分离出一种不同于甘油三酯酸、含有半乳糖和n -乙酰氨基葡萄糖的多糖。在链霉菌的发育过程中，肽聚糖的数量保持不变，壁藻酸的数量减少，多糖的数量增加。在链霉菌细胞壁的壁石酸和多糖的组成中存在的氨基糖与在夹竹桃霉素的结构中存在的氨基糖之间的相关性被证明。这可能与生物体的生理特征有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology

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