Whether reactivation of granuloma inguinale can be a possibility in a person living with HIV?

Abstract

Granuloma inguinale is one of the ulcerative sexually transmitted infections (STIs), and the incidence is very low almost worldwide. When it is associated with HIV infection, it poses a real challenge to the physician as the recommended guidelines often won't work well. Granuloma inguinale is comparatively less contagious than other STIs as the conjugal infection and vertical transmission are rare. In the present case, the patient denied any extramarital contact after marriage (for 32 years). His wife was not having any genital lesion, and their contacts were protective one. It raises the suspicion whether there could be a possibility of a latent infection in the presence of HIV as that of tuberculosis, CMV infection, and herpes zoster infection.