{"title":"Adolescent nutritional influences on the brain: implications for eating behaviors","authors":"Mary Lazzaro , Austin M. Mills , Emily E. Noble","doi":"10.1016/j.neuropharm.2025.110570","DOIUrl":null,"url":null,"abstract":"<div><div>Adolescence represents a life stage in which vast physiological and neuroendocrine changes contribute to rapid growth and development. Throughout this transition from childhood to adulthood, the adolescent brain is in a critical developmental period. This is especially true for the prefrontal cortex and hippocampus, essential areas for executive functioning. The formation of lasting synaptic connections and dynamic plasticity within the adolescent brain make it especially vulnerable to environmental insults, such as a poor-quality diet. Herein, we review research pertaining to the period of adolescence with respect to food intake control as well as the impact of the modern food environment on the development of the prefrontal cortex and hippocampus and discuss implications for ingestive behaviors throughout rest of life.</div></div>","PeriodicalId":19139,"journal":{"name":"Neuropharmacology","volume":"278 ","pages":"Article 110570"},"PeriodicalIF":4.6000,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuropharmacology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S002839082500276X","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Adolescence represents a life stage in which vast physiological and neuroendocrine changes contribute to rapid growth and development. Throughout this transition from childhood to adulthood, the adolescent brain is in a critical developmental period. This is especially true for the prefrontal cortex and hippocampus, essential areas for executive functioning. The formation of lasting synaptic connections and dynamic plasticity within the adolescent brain make it especially vulnerable to environmental insults, such as a poor-quality diet. Herein, we review research pertaining to the period of adolescence with respect to food intake control as well as the impact of the modern food environment on the development of the prefrontal cortex and hippocampus and discuss implications for ingestive behaviors throughout rest of life.
期刊介绍:
Neuropharmacology publishes high quality, original research and review articles within the discipline of neuroscience, especially articles with a neuropharmacological component. However, papers within any area of neuroscience will be considered. The journal does not usually accept clinical research, although preclinical neuropharmacological studies in humans may be considered. The journal only considers submissions in which the chemical structures and compositions of experimental agents are readily available in the literature or disclosed by the authors in the submitted manuscript. Only in exceptional circumstances will natural products be considered, and then only if the preparation is well defined by scientific means. Neuropharmacology publishes articles of any length (original research and reviews).