Transcatheter edge-to-edge repair of the systemic atrioventricular valve in a patient with congenitally corrected transposition of the great arteries and dextrocardia

Abstract

A 33-year-old male with congenitally corrected transposition of the great arteries (ccTGA), dextrocardia and situs solitus presented with dyspnea at rest, classified as New York Heart Association (NYHA) class IV, in the context of severe systemic atrioventricular valve (SAVV) regurgitation, and impaired systolic function of the systemic morphologically right ventricle. Due to high surgical risk, the Heart Team opted for a transcatheter edge-to-edge repair (TEER) using a PASCAL ACE device. The procedure successfully reduced regurgitation from severe to mild, resulting in symptomatic improvement and recovery to NYHA class I at six-month follow-up. This case highlights the feasibility of TEER as a minimally invasive alternative in selected patients with ccTGA and systemic AV valve regurgitation.