Positive correlation of prevalence of Angiostongylis cantonensis in Parmarion martensi (semi-slug) with higher human neuroangiostrongyliasis (rat lungworm disease) caseloads in east Hawai'i Island.
S I Jarvi, L M Kaluna, K Howe, K D Fiedler, C T Vlautin, M G Severino, J Botticelli, R McHugh
{"title":"Positive correlation of prevalence of Angiostongylis cantonensis in Parmarion martensi (semi-slug) with higher human neuroangiostrongyliasis (rat lungworm disease) caseloads in east Hawai'i Island.","authors":"S I Jarvi, L M Kaluna, K Howe, K D Fiedler, C T Vlautin, M G Severino, J Botticelli, R McHugh","doi":"10.1016/j.ijpara.2025.06.004","DOIUrl":null,"url":null,"abstract":"<p><p>Toward a better understanding of Angiostrongylus cantonensis infection within intermediate gastropod hosts, we evaluated prevalence of A. cantonensis in gastropods from east Hawai'i Island and Kaua'i, and used this data to begin to explore how gastropod infection may relate to human neuroangiostrongyliasis patterns in these regions. An overall infection prevalence of 43.3% was found among four of the eight species tested. Of the seven species tested from Kaua'i (n = 170) 12.9% were positive among three species, and of the two slug species tested from east Hawai'i island (n = 320) 59.4% tested positive. In east Hawai'i Island, parasite prevalence was significantly greater in Parmarion martensi (84.4%) than in Veronicella cubensis (10.2%) (P < 0.001), however, infection rates in V. cubensis on east Hawai'i Island did not significantly differ than in V. cubensis tested on Kaua'i (11.6%) (P = 0.878). Comparing parasite loads among regions within east Hawai'i Island, parasite loads were significantly greater in P. martensi from Pāhoa than in those from Hilo (P < 0.001) and in those from Kea'au than Hilo (P = 0.004), and significantly differed among these districts (P < 0.001). Based on zip code tabulation areas (ZCTA) in east Hawai'i Island, prevalence of infection of slugs collected from ZCTA's with 1-5 human cases of neuroangiostrongyliasis was 9.5%, in ZCTA's with 11-15 human cases averaged 65.7%, and in ZCTA's with 16-31 cases was 67.3%. Slug infection prevalence appears higher in ZCTA's with higher human neuroangiostrongyliasis caseloads, at least in these regions in east Hawai'i Island (P < 0.001).</p>","PeriodicalId":13725,"journal":{"name":"International journal for parasitology","volume":" ","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal for parasitology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.ijpara.2025.06.004","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PARASITOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Toward a better understanding of Angiostrongylus cantonensis infection within intermediate gastropod hosts, we evaluated prevalence of A. cantonensis in gastropods from east Hawai'i Island and Kaua'i, and used this data to begin to explore how gastropod infection may relate to human neuroangiostrongyliasis patterns in these regions. An overall infection prevalence of 43.3% was found among four of the eight species tested. Of the seven species tested from Kaua'i (n = 170) 12.9% were positive among three species, and of the two slug species tested from east Hawai'i island (n = 320) 59.4% tested positive. In east Hawai'i Island, parasite prevalence was significantly greater in Parmarion martensi (84.4%) than in Veronicella cubensis (10.2%) (P < 0.001), however, infection rates in V. cubensis on east Hawai'i Island did not significantly differ than in V. cubensis tested on Kaua'i (11.6%) (P = 0.878). Comparing parasite loads among regions within east Hawai'i Island, parasite loads were significantly greater in P. martensi from Pāhoa than in those from Hilo (P < 0.001) and in those from Kea'au than Hilo (P = 0.004), and significantly differed among these districts (P < 0.001). Based on zip code tabulation areas (ZCTA) in east Hawai'i Island, prevalence of infection of slugs collected from ZCTA's with 1-5 human cases of neuroangiostrongyliasis was 9.5%, in ZCTA's with 11-15 human cases averaged 65.7%, and in ZCTA's with 16-31 cases was 67.3%. Slug infection prevalence appears higher in ZCTA's with higher human neuroangiostrongyliasis caseloads, at least in these regions in east Hawai'i Island (P < 0.001).
期刊介绍:
International Journal for Parasitology offers authors the option to sponsor nonsubscriber access to their articles on Elsevier electronic publishing platforms. For more information please view our Sponsored Articles page. The International Journal for Parasitology publishes the results of original research in all aspects of basic and applied parasitology, including all the fields covered by its Specialist Editors, and ranging from parasites and host-parasite relationships of intrinsic biological interest to those of social and economic importance in human and veterinary medicine and agriculture.