Comprehensive Bibliometric Analysis of Prediction Models for HCC: Current Trends and Future Prospects.

IF 1.6 Q4 ONCOLOGY

Journal of Gastrointestinal Cancer Pub Date : 2025-06-19 DOI:10.1007/s12029-025-01249-1

Dong Li, Jingchao Sun, Xifeng Fu, Fei Gao

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引用次数: 0

Abstract

Background: Hepatocellular carcinoma (HCC) is the most common primary malignant liver tumor, with rising incidence and mortality rates posing a significant threat to global public health. Accurate prediction of liver cancer occurrence and progression is essential for improving patient prognosis. This study uses bibliometric methods to analyze the current state and future trends in liver cancer prediction research.

Methods: A search was conducted in the Web of Science (WOS) database on October 22, 2023, identifying 1092 articles on liver cancer prediction. These articles were quantitatively analyzed using CiteSpace 6.2 software, with a focus on research hotspots, authors, countries, and keywords.

Results: The study involved 114 countries, 4254 institutions, and 280 journals, with 48,788 citations. China (826 papers) and the USA (96 papers) dominate the field. Leading institutions include Sun Yat-sen University, Fudan University, Zhejiang University, and Yonsei University. The most cited journals were Hepatology (2209 citations) and Journal of Hepatology (946 citations). Frontiers in Oncology had the highest H-index (14). Key authors include Kim Seung Up (23 papers) and Ahn Sang Hoon (H-index = 14). Early research focused on risk factors and staging, while recent studies emphasize DNA methylation, immune microenvironments, and tumor metastasis. Future research will focus on multi-omics data integration and AI-driven predictive model optimization.

Conclusion: This study provides a comprehensive overview of liver cancer prediction research, highlighting key trends and the potential of multi-omics data and machine learning to enhance predictive models and clinical outcomes.

查看原文本刊更多论文

HCC预测模型的综合文献计量学分析：当前趋势和未来展望。

背景：肝细胞癌（HCC）是最常见的原发性恶性肝脏肿瘤，其发病率和死亡率不断上升，对全球公共卫生构成重大威胁。准确预测肝癌的发生和进展对改善患者预后至关重要。本研究采用文献计量学方法分析肝癌预测研究的现状及未来趋势。方法：于2023年10月22日在Web of Science （WOS）数据库中检索有关肝癌预测的文献1092篇。采用CiteSpace 6.2软件对论文进行定量分析，重点对研究热点、作者、国家和关键词进行分析。结果：该研究涉及114个国家，4254个机构，280种期刊，引用48,788次。中国（826篇）和美国（96篇）占据主导地位。主要院校包括中山大学、复旦大学、浙江大学和延世大学。被引频次最多的期刊是《肝病学》（2209次）和《肝病学杂志》（946次）。Frontiers in Oncology的h指数最高，为14。主要作者有金承业（23篇）和安相勋（H-index = 14）。早期的研究侧重于危险因素和分期，而最近的研究强调DNA甲基化、免疫微环境和肿瘤转移。未来的研究将集中在多组学数据集成和人工智能驱动的预测模型优化上。结论：本研究提供了肝癌预测研究的全面概述，突出了多组学数据和机器学习在增强预测模型和临床结果方面的关键趋势和潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Gastrointestinal Cancer ONCOLOGY-

CiteScore

3.80

自引率

0.00%

发文量

121

期刊介绍： The Journal of Gastrointestinal Cancer is a multidisciplinary medium for the publication of novel research pertaining to cancers arising from the gastrointestinal tract.The journal is dedicated to the most rapid publication possible.The journal publishes papers in all relevant fields, emphasizing those studies that are helpful in understanding and treating cancers affecting the esophagus, stomach, liver, gallbladder and biliary tree, pancreas, small bowel, large bowel, rectum, and anus. In addition, the Journal of Gastrointestinal Cancer publishes basic and translational scientific information from studies providing insight into the etiology and progression of cancers affecting these organs. New insights are provided from diverse areas of research such as studies exploring pre-neoplastic states, risk factors, epidemiology, genetics, preclinical therapeutics, surgery, radiation therapy, novel medical therapeutics, clinical trials, and outcome studies.In addition to reports of original clinical and experimental studies, the journal also publishes: case reports, state-of-the-art reviews on topics of immediate interest or importance; invited articles analyzing particular areas of pancreatic research and knowledge; perspectives in which critical evaluation and conflicting opinions about current topics may be expressed; meeting highlights that summarize important points presented at recent meetings; abstracts of symposia and conferences; book reviews; hypotheses; Letters to the Editors; and other items of special interest, including:Complex Cases in GI Oncology: This is a new initiative to provide a forum to review and discuss the history and management of complex and involved gastrointestinal oncology cases. The format will be similar to a teaching case conference where a case vignette is presented and is followed by a series of questions and discussion points. A brief reference list supporting the points made in discussion would be expected.