Minimally invasive coronary bypass grafting for treating multivessel coronary disease: A single-center prospective pilot study

IF 1.9

JTCVS open Pub Date : 2025-06-01 DOI:10.1016/j.xjon.2025.03.030

Tong Ding MD, PhD, Yichen Gong MD, Yuanhao Fu MD, Zhongqi Cui MD, Song Wu MD, Wei Yang MD, Hang Yang MD, Hong Zhao MD, Haibo Feng MD, Huiping Zheng MD, Luyu Meng MD, Rui Guo MD, Huijin Han BS, Yunpeng Ling MD

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Abstract

Objectives

The study sought to explore the characteristics and outcomes of patients undergoing clinically indicated minimally invasive cardiac surgery—coronary artery bypass grafting (MICS-CABG) and off-pump coronary artery bypass for MICS-CABG eligible multivessel disease, to inform the design of a confirmatory comparative effectiveness trial.

Methods

Over 30 months, 245 MICS-CABG and 158 off-pump coronary artery bypass participants were enrolled. Health-related quality-of-life was assessed using the 36-Item Short-Form Health Survey and Seattle Angina Questionnaire. The primary end point was the score on the physical component summary and mental component summary subscale of the 36-Item Short-Form Health Survey (on which scores range from 0 to 100, with higher scores indicating better health status).

Results

The score on the Physical Component Summary-United States subscale of the 36-Item Short-Form Health Survey increased to a greater extent with MICS-CABG than with off-pump coronary artery bypass at both 7 and 30 days (P = .002 and P = .001, respectively), as well as Physical Component Summary-Hong Kong subscale (MICS-CABG and off-pump coronary artery bypass: P = .002 and P < .001, respectively). The mental component summary subscale of the 36-Item Short-Form Health Survey in either the United States or Hong Kong and all 5 domains of Seattle Angina Questionnaire score were similar between the 2 groups throughout the follow-up period.

Conclusions

MICS-CABG, an emerging modality for treating multivessel coronary disease, yields an improved 7- and 30-day physical function than off-pump coronary artery bypass. Moreover, both strategies resulted in similar significant relief from angina over 12 months. A randomized controlled trial is warranted to compare the efficacy of these 2 revascularization strategies. (Prospective Cohort Study on Minimal Invasive Coronary Surgery: NCT04267835).

查看原文本刊更多论文

微创冠状动脉旁路移植术治疗多支冠状动脉疾病：一项单中心前瞻性先导研究

目的：本研究旨在探讨微创心脏手术-冠状动脉旁路移植术（MICS-CABG）和非泵送冠状动脉旁路移植术治疗符合MICS-CABG条件的多血管疾病患者的特点和结果，为设计一项验证性比较疗效试验提供信息。方法在30个月的时间里，纳入245名MICS-CABG和158名非体外循环冠状动脉搭桥术参与者。健康相关生活质量评估采用36项简短健康调查和西雅图心绞痛问卷。主要终点是36项简短健康调查的身体成分总结和精神成分总结子量表的得分（得分范围从0到100，得分越高表明健康状况越好）。结果在第7天和第30天，MICS-CABG组的36项简短健康调查的Physical Component Summary-United subscale （P = 0.002和P = 0.001）以及Physical Component Summary-Hong subscale （MICS-CABG和非体外循环冠状动脉搭桥术：P = 0.002和P <）得分均高于非体外循环冠状动脉搭桥术(P = 0.002和P <；措施,分别)。在美国和香港的36项简短健康调查的心理成分总结子量表和西雅图心绞痛问卷的5个领域得分在随访期间在两组之间相似。结论smics - cabg是治疗多支冠状动脉疾病的一种新兴方式，与非体外循环冠状动脉搭桥术相比，其7天和30天的身体功能都有所改善。此外，两种策略在12个月内对心绞痛的缓解效果相似。需要一项随机对照试验来比较这两种血运重建策略的疗效。（微创冠状动脉手术前瞻性队列研究：NCT04267835）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

JTCVS open

CiteScore

1.70

自引率

0.00%

发文量