Virtual versus in-person ROSE program (La Luz) as universal prevention for perinatal depression: Protocol for a randomized controlled trial in a safety net hospital

IF 1.9 3区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Daphne Y. Liu , Nicholas S. Perry , Catherine H. Demers , Jennifer S. Hyer , Anely Alamo , Paige Vuksanovich , Nandi Dube , Erin R. Flanagan , Robert J. Gallop , Galena K. Rhoades , Elysia Poggi Davis
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引用次数: 0

Abstract

Perinatal depression disproportionally affects underserved communities, who need effective and accessible prevention programs. Reach Out, Stay strong, Essentials for new mothers (ROSE) has demonstrated effectiveness in preventing postpartum depression in underserved populations when delivered in person. This ongoing randomized controlled trial (RCT) tests the novel virtual implementation of ROSE as universal prevention in a Federally Qualified Health Center setting. We adopted the name, La Luz, for ROSE to be culturally relevant to our population. Pregnant individuals <30 gestational weeks (target N = 900) are randomized to either the virtual or in-person La Luz program, which consists of four 90-min group sessions. Groups are offered in English and Spanish, based on participants' preference. Participants complete surveys at seven timepoints: before program, 28 gestational weeks, 35 gestational weeks, and 6-weeks, 3-months, 6-months, and 12-months postpartum. Primary outcomes are postpartum depression severity measured by the 20-item Symptom Checklist (SCL-20) and 10-item Center of Epidemiologic Studies Depression Scale (CESD-10). We will perform intent-to-treat analysis to test whether virtual La Luz is non-inferior to in-person La Luz. This study also evaluates implementation process and outcomes of both modalities of La Luz to inform the development of an implementation toolkit. This RCT contributes to our knowledge of perinatal depression prevention and addresses access barriers for underserved populations. If effectiveness of virtual La Luz is demonstrated, the new evidence for a scalable low-cost prevention can be used to reduce perinatal depression and offer accessible treatment options for people who face significant barriers to care. Clinicaltrials.gov registration identifier: NCT05766475.
虚拟与面对面的ROSE项目(La Luz)作为围产期抑郁症的普遍预防:一个安全网医院的随机对照试验方案
围产期抑郁症不成比例地影响到服务不足的社区,他们需要有效和可获得的预防方案。伸出援手,保持坚强,新妈妈必需品(ROSE)在亲自交付时,在服务不足的人群中证明了预防产后抑郁症的有效性。这项正在进行的随机对照试验(RCT)测试了在联邦合格的健康中心设置中,ROSE作为普遍预防的新型虚拟实施。我们采用了La Luz这个名字,因为ROSE在文化上与我们的人口相关。怀孕的人
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来源期刊
CiteScore
3.70
自引率
4.50%
发文量
281
审稿时长
44 days
期刊介绍: Contemporary Clinical Trials is an international peer reviewed journal that publishes manuscripts pertaining to all aspects of clinical trials, including, but not limited to, design, conduct, analysis, regulation and ethics. Manuscripts submitted should appeal to a readership drawn from disciplines including medicine, biostatistics, epidemiology, computer science, management science, behavioural science, pharmaceutical science, and bioethics. Full-length papers and short communications not exceeding 1,500 words, as well as systemic reviews of clinical trials and methodologies will be published. Perspectives/commentaries on current issues and the impact of clinical trials on the practice of medicine and health policy are also welcome.
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