Fast-field-echo resembling a CT using restricted echo-spacing (FRACTURE) can differentiate osteophytes from disc herniations in patients with cervical radiculopathy: a feasibility study

IF 3.2 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology Pub Date : 2025-06-16 DOI:10.1016/j.ejrad.2025.112243

Dongmei Jiang , Junhuan Hong , Shuyi Lei , Qiang Weng , Ruiquan Chen , Xiance Zhao , Dejun She , Dairong Cao

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引用次数: 0

Abstract

Objective

To evaluate the diagnostic performance of fast-field-echo resembling a CT using restricted echo-spacing (FRACTURE) for differentiating cervical osteophytes and disc herniations.

Materials and methods

Patients suspected of cervical radiculopathy (CR) with FRACTURE, conventional MRI, and CT scans were retrospectively included between October 17, 2023 and July 24, 2024. A total of 43 patients (20 women, 23 men; mean age, 57.3 ± 1.8 years) were enrolled and 516 intervertebral foramina were analyzed from bilateral C2/3 to C7/T1 on sagittal images. CT combined with MRI was the reference standard to identify osteophytes and disc herniations. The diagnostic performance of different images for identifying osteophytes and disc herniations was evaluated. The inter-modality differences, correlations, and agreements were assessed by measuring the sizes of osteophytes and disc herniations.

Results

For osteophytes, the sensitivity and specificity of FRACTURE were 94.7 % and 98.9 %, respectively; the area under the curve (AUC) of FRACTURE (AUC = 0.968) was significantly higher than that of T1WI (AUC = 0.688) and T2WI (AUC = 0.738). For disc herniations, the sensitivity and specificity of FRACTURE were 95.6 % and 99.2 %, respectively; the AUC of FRACTURE (AUC = 0.974) was also significantly higher than that of T1WI (AUC = 0.855) and T2WI (AUC = 0.864). A strong correlation (R² = 0.84) and an excellent agreement (ICC = 0.917) were achieved between FRACTURE and CT for osteophytes measurements. Strong correlations and excellent agreements were also obtained for disc herniations measurements between FRACTURE and T1WI (R² = 0.82, ICC = 0.990)/T2WI (R² = 0.92, ICC = 0.951).

Conclusions

FRACTURE enables the reliable differentiation of osteophytes and disc herniations in patients with CR.

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利用有限回声间隔（骨折）类似CT的快速场回波可以区分颈椎神经根病患者的骨赘和椎间盘突出：一项可行性研究

目的探讨限制回波间隔（骨折）与CT相似的快速场回波对颈椎骨赘和椎间盘突出的诊断价值。材料与方法回顾性分析2023年10月17日至2024年7月24日期间怀疑颈椎神经根病（CR）合并骨折的患者，进行常规MRI和CT扫描。共43例患者(女性20例，男性23例；平均年龄（57.3±1.8岁），在矢状面图像上分析双侧C2/3至C7/T1的516个椎间孔。CT结合MRI是鉴别骨赘和椎间盘突出的参考标准。评价不同影像对骨赘和椎间盘突出的诊断效果。通过测量骨赘和椎间盘突出的大小来评估模态间的差异、相关性和一致性。结果骨折对骨赘的敏感性和特异性分别为94.7%和98.9%；骨折的曲线下面积（AUC）（AUC = 0.968）明显高于T1WI （AUC = 0.688）和T2WI （AUC = 0.738）。对于椎间盘突出，骨折的敏感性和特异性分别为95.6%和99.2%；骨折的AUC （AUC = 0.974）也显著高于T1WI （AUC = 0.855）和T2WI （AUC = 0.864）。骨折和CT对骨赘的测量结果具有很强的相关性（R2 = 0.84）和极好的一致性（ICC = 0.917）。骨折与T1WI (R2 = 0.82, ICC = 0.990)/T2WI （R2 = 0.92, ICC = 0.951）之间的椎间盘突出测量也获得了很强的相关性和极好的一致性。结论骨折可以可靠地鉴别骨赘和椎间盘突出。

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来源期刊

European Journal of Radiology 医学-核医学

CiteScore

6.70

自引率

3.00%

发文量

398

审稿时长

42 days

期刊介绍： European Journal of Radiology is an international journal which aims to communicate to its readers, state-of-the-art information on imaging developments in the form of high quality original research articles and timely reviews on current developments in the field. Its audience includes clinicians at all levels of training including radiology trainees, newly qualified imaging specialists and the experienced radiologist. Its aim is to inform efficient, appropriate and evidence-based imaging practice to the benefit of patients worldwide.