Ferrocene-modified nickel MOF: A robust heterogeneous catalyst for deamination-driven CO cross-coupling

Abstract

Deamination-assisted CO cross-coupling reactions remain a significant challenge in organic synthesis. Herein, we report the synthesis of a novel ferrocene-functionalized bimetallic metal-organic framework (Ni-Fc-BDC MOF) as an efficient heterogeneous catalyst. The catalyst demonstrates excellent activity in CO bond formation between o-phenylenediamine and benzyl alcohol, delivering high yields and broad substrate compatibility. Its versatility is evident in its ability to efficiently catalyze reactions involving substrates with electron-donating, electron-withdrawing, and sterically hindered groups. Comprehensive characterization reveals its structural stability and catalytic efficiency, providing a sustainable approach to organic transformations. This study underscores the promise of Ni-Fc-BDC as a robust and versatile platform, offering significant potential for advancing future catalytic applications.