Davide Marenduzzo, Aidan T. Brown, Craig W. Miller, Graeme J. Ackland
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引用次数: 0
Abstract
We study the SIRS epidemic model, both analytically and on a square lattice. The analytic model has two stable solutions, post outbreak/epidemic (no infected, ) and the endemic state (constant number of infected: ). When the model is implemented with noise, or on a lattice, a third state is possible, featuring regular oscillations. This is understood as a cycle of boom and bust, where an epidemic sweeps through, and dies out leaving a small number of isolated infecteds. As immunity wanes, herd immunity is lost throughout the population and the epidemic repeats. The key result is that the oscillation is an intrinsic feature of the system itself, not driven by external factors such as seasonality or behavioural changes. The model shows that non-seasonal oscillations, such as those observed for the omicron COVID variant, need no additional explanation such as the appearance of more infectious variants at regular intervals or coupling to behaviour. We infer that the loss of immunity to the SARS-CoV-2 virus occurs on a timescale of about ten weeks.
期刊介绍:
The Journal of Theoretical Biology is the leading forum for theoretical perspectives that give insight into biological processes. It covers a very wide range of topics and is of interest to biologists in many areas of research, including:
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