Pediatric methamphetamine poisoning: Case report of a one-year-old child.

Esat Barut, Kemal Barut
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Abstract

Methamphetamine is a derivative of amphetamine and is widely abused across the globe. It is highly addictive and acts as a potent stimulant of the central nervous system (CNS). Due to its lipophilic nature, methamphetamine easily crosses the blood-brain barrier, leading to significant neurological dysfunctions and even neuronal degeneration. The clinical signs and symptoms of methamphetamine intoxication can vary considerably depending on factors such as the dose ingested, route of administration, duration of exposure (acute and/or chronic), and method of use. Common clinical manifestations include euphoria, increased energy, insomnia, anxiety, substance-induced psychosis, decreased appetite, weight loss, heightened self-confidence, increased libido, fever, tachycardia, sweating, hypertension, tremors, mydriasis, blurred vision, and seizures. Children are particularly vulnerable, as their metabolism and nervous systems are more sensitive compared to adults, making the toxic effects more pronounced. Accidental ingestion of drugs and other substances is a frequent occurrence in pediatric populations and can lead to severe health complications. Therefore, it is crucial for healthcare professionals to promptly and accurately evaluate and manage such poisoning cases. This case report presents the clinical findings, diagnostic process, and treatment management of a one-year-old male child who accidentally ingested crystal methamphetamine orally. Additionally, the report highlights key aspects of effective case management, emphasizes preventive measures to reduce the risk of accidental drug and substance ingestion in children, and aims to raise awareness on this issue.

小儿甲基苯丙胺中毒:1例1岁儿童报告。
甲基苯丙胺是安非他明的衍生物,在全球范围内被广泛滥用。它是高度成瘾性的,并作为中枢神经系统(CNS)的强效兴奋剂。由于其亲脂性,甲基苯丙胺很容易穿过血脑屏障,导致严重的神经功能障碍,甚至神经元变性。甲基苯丙胺中毒的临床体征和症状可因摄入剂量、给药途径、暴露时间(急性和/或慢性)和使用方法等因素而有很大差异。常见的临床表现包括兴奋、精力充沛、失眠、焦虑、药物性精神病、食欲减退、体重减轻、自信心增强、性欲增强、发热、心动过速、出汗、高血压、震颤、瞳孔模糊和癫痫发作。儿童尤其容易受到伤害,因为他们的新陈代谢和神经系统比成年人更敏感,因此毒性作用更加明显。意外摄入药物和其他物质是儿科人群中经常发生的事情,并可能导致严重的健康并发症。因此,医疗保健专业人员及时准确地评估和处理此类中毒病例至关重要。本病例报告介绍1岁男童意外口服甲基苯丙胺晶体的临床表现、诊断过程和治疗管理。此外,该报告强调了有效病例管理的关键方面,强调了减少儿童意外摄入药物和物质风险的预防措施,并旨在提高对这一问题的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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