A Novel Same Day Discharge Program After Pulmonary Wedge Resection

David Sahai BSc , Richard C. Chaulk MD , Richard Malthaner MD , Mehdi Qiabi MD , Dalilah Fortin MD , Richard Inculet MD , Rahul Nayak MD
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Abstract

Background

The current practice for patients undergoing minimally invasive pulmonary wedge resection (MIS-PWR) is to remain in hospital with a chest tube (CT) in situ for at least 24 hours. There exists emerging evidence that patients typically do not encounter significant complications during this period. However, this has not been studied prospectively.

Research Question

Is it feasible and safe for patients to undergo early CT removal and same day discharge (SDD) after elective MIS-PWR?

Study Design and Methods

We conducted a nonrandomized prospective clinical trial in 2 phases to assess early CT removal and SDD after elective MIS-PWR. Phase 1 focused on the safety of early CT removal with patients undergoing removal at 4 hours postoperatively. Phase 2 evaluated both early CT removal and SDD. The primary outcomes were rate of successful early CT removal and the rate of successful SDD.

Results

In phase 1, a total of 51 patients were enrolled (intervention group: n = 31, control group: n = 20). In the intervention group, 22 (71%) had early removal of CT. Patients who underwent early CT removal in this phase had a significantly shorter median length of hospital stay in days (2.0 in control group vs 1.0 in intervention group; P = .0185) without significant differences in postoperative day 1 and 30 complications or return to the hospital. In phase 2, a total of 43 patients were enrolled (intervention group: n = 23, control group: n = 20). In the intervention group, 17 (74%) had early CT removal and 14 (61%) successfully underwent SDD. There were no significant differences noted in postoperative day 1 and 30 complications or early return to hospital. No patients required pleural reintervention after early CT removal.

Interpretation

Our results indicate that select patients undergoing MIS-PWR can safely undergo early CT removal and can be safely discharged on the day of surgery.

Clinical Trial Registration

ClinicalTrials.gov; No.: NCT05067738; URL: www.clinicaltrials.gov
一种新的肺楔形切除术后当日出院方案
背景:目前接受微创肺楔形切除术(MIS-PWR)的患者的做法是在原位胸管(CT)下住院至少24小时。有新的证据表明,在此期间,患者通常不会遇到严重的并发症。然而,这还没有前瞻性的研究。选择性MIS-PWR术后患者早期CT切除和当日出院(SDD)是否可行和安全?研究设计和方法我们进行了一项非随机前瞻性临床试验,分为两个阶段来评估选择性MIS-PWR术后早期CT切除和SDD。第一阶段的重点是患者术后4小时进行早期CT切除的安全性。二期评估早期CT切除和SDD。主要结果是早期CT切除成功率和SDD成功率。结果第一阶段共纳入51例患者,其中干预组31例,对照组20例。干预组22例(71%)早期行CT切除。在该阶段接受早期CT切除的患者的中位住院天数(对照组2.0天vs干预组1.0天)显著缩短;P = 0.0185),术后第1天和第30天的并发症或复诊率无显著差异。第二阶段共纳入43例患者(干预组23例,对照组20例)。干预组17例(74%)早期CT切除,14例(61%)成功行SDD。术后第1天、第30天并发症及早期返院率无显著差异。早期CT切除后无患者需要胸膜再干预。我们的研究结果表明,接受MIS-PWR的患者可以安全地进行早期CT切除,并可以在手术当天安全出院。临床试验注册网站clinicaltrials .gov;否。: NCT05067738;URL: www.clinicaltrials.gov
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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