Dementia in Sub-Saharan Africa: Risk factors, public perception, and management approaches

Zemichael Getu Alemayehu , Biruk Demisse Ayalew , Brook Lelisa Sime , Tsimona Dinku Bonger , Yonatan Abbawa Zewdie , Abenezer Shiferaw Keraga , Henok Wolde Nida , Temesgen Mamo Sharew , Beamlak Getachew Woldeselassie , Mateyas Yohannes Melaku , Biniyam Alemayehu Ayele
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Abstract

Dementia is becoming a major public health problem in Sub-Saharan Africa (SSA), with prevalence increasing due to demographic transitions, increasing life expectancy, and increasing prevalence of non-communicable diseases. This commentary synthesizes the latest data on the epidemiology, risk factors, public perception, and management approaches for dementia in SSA, noting that although worldwide rates of dementia are increasing, SSA will experience the highest growth, which, with the current rate of increase, is projected to triple by 2050. SSA prevalence rates vary widely from 2.3 % to as high as 20 %, predominantly because of methodological discrepancies, lack of identification, and limited access to medical care. Incidence figures are also weak and mostly restricted to a few countries, thus potentially underestimating the true regional burden. The identified risk factors include age, gender, low educational attainment, untreated hypertension, diabetes, infectious diseases, including causes of HIV and cerebral malaria, and specific genetic predispositions, with low educational status being the most powerful modifiable factor. Stigma and misconceptions often delay diagnosis and contribute to under-reporting, compounding the burden on affected families. The sub-optimal healthcare system, lack of culturally appropriate diagnostics, and national fragmentation of epidemiological data make the situation of SSA more complex. The commentary emphasizes the importance of raising awareness, data collection method refinement, and culturally informed approaches to guide policy-making, promote research, and enhance the prevention and management of dementia in SSA, to develop locally-suited interventions to address the growing dementia epidemic.
撒哈拉以南非洲的痴呆症:风险因素、公众认知和管理方法
痴呆症正在成为撒哈拉以南非洲(SSA)的一个主要公共卫生问题,由于人口结构的转变、预期寿命的延长和非传染性疾病的日益流行,痴呆症的患病率不断上升。这篇评论综合了SSA痴呆症的流行病学、风险因素、公众认知和管理方法的最新数据,指出尽管全球痴呆症发病率正在上升,但SSA将经历最高的增长,按照目前的增长速度,预计到2050年将增长两倍。SSA患病率差异很大,从2.3 %到高达20% %,主要原因是方法上的差异,缺乏识别,以及获得医疗保健的机会有限。发病率数字也很弱,而且大多局限于少数国家,因此可能低估了真正的区域负担。确定的风险因素包括年龄、性别、受教育程度低、未经治疗的高血压、糖尿病、传染病,包括艾滋病毒和脑型疟疾的病因,以及特定的遗传倾向,其中受教育程度低是最有力的可改变因素。污名化和误解往往会延误诊断,导致报告不足,加重受影响家庭的负担。次优的医疗保健系统,缺乏文化上合适的诊断方法,以及国家流行病学数据的碎片化使得SSA的情况更加复杂。该评论强调了提高认识、改进数据收集方法和了解文化的方法的重要性,以指导决策、促进研究和加强SSA的痴呆症预防和管理,并制定适合当地的干预措施,以应对日益严重的痴呆症流行病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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