Stigmatization, Medication Adherence and Resilience Among Recently Diagnosed People Living With HIV/AIDS (PLWHA): A Mixed-Method Study.

Public health challenges Pub Date : 2025-02-24 eCollection Date: 2025-03-01 DOI:10.1002/puh2.70036

Emmanuel O Adesuyi, Cynthia A Attah, Oluwatosin A Ige, Confidence C Attamah, Khadijah A Jimoh, Opeoluwa O Olabode, Oluwadamilare Akingbade, Ayobami O Adeagbo, Rafiat Akinokun, Esther Ilesanmi, Mary I Oyeleke, Abiodun E Dairo, Yetunde O Tola

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Abstract

Aim and objectives: To investigate the level of stigma, medication adherence and resilience among recently diagnosed people living with HIV/AIDS (PLWHA) and explore the relationship between medication adherence, stigmatization and resilience.

Design/method: This is a convergent-parallel mixed-method design involving both qualitative and quantitative research methodologies. The quantitative aspect utilized a cross-sectional design among 200 PLWHA at the anti-retroviral therapy clinic of the Lagos University Teaching Hospital, Lagos, Nigeria, whereas the qualitative part entailed semi-structured, in-depth interviews of 26 PLWHA. Spearman's rho correlation was used to explore the relationship between medication adherence, stigmatization and resilience, and qualitative data were analysed using thematic analysis.

Result: Four themes emerged from the qualitative analysis, including building resilience, experiences relating to diagnosis, experiences related to treatment and factors facilitating medication adherence. Overall, 113 (57%) experienced a high level of stigma, 149 (76%) reported high medication adherence, and above average 115 (57.2%) demonstrated high resilience.

Conclusion: In this study, PLWHA in Nigeria who recently received their diagnosis experienced a high level of stigma, resilience and medication adherence. However, nearly one-third of the participants were non-adherent to medication due to several reasons. This noteworthy proportion of non-adherence needs to be addressed while improving resilience and reducing stigmatization.

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污名化，药物依从性和恢复力在新近诊断的艾滋病毒/艾滋病患者（PLWHA）：一项混合方法研究。

目的和目的：调查新近诊断的HIV/AIDS感染者（PLWHA）的耻辱感、药物依从性和恢复力水平，并探讨药物依从性、耻辱感和恢复力之间的关系。设计/方法：这是一种融合并行的混合方法设计，涉及定性和定量研究方法。定量方面对尼日利亚拉各斯拉各斯大学教学医院抗逆转录病毒治疗诊所的200名艾滋病感染者进行了横断面设计，而定性部分则对26名艾滋病感染者进行了半结构化的深入访谈。采用Spearman’s rho相关分析药物依从性、污名化和心理韧性之间的关系，并采用专题分析对定性数据进行分析。结果：从定性分析中出现了四个主题，包括建立弹性，与诊断相关的经验，与治疗相关的经验和促进药物依从性的因素。总体而言，113人（57%）经历了高度的耻辱感，149人（76%）报告了高度的药物依从性，高于平均水平的115人（57.2%）表现出高度的适应能力。结论：在本研究中，尼日利亚新近接受诊断的艾滋病感染者经历了高度的污名化、复原力和药物依从性。然而，由于一些原因，近三分之一的参与者没有坚持服药。需要在提高复原力和减少污名化的同时解决这一值得注意的不遵守比例问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Public health challenges

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