Drug prescribing pattern in upper respiratory tract infections among the pediatric population attending outpatient clinics in pediatric hospitals.

Amir F Kamal, Eman A Abdelaziz, Veronia F Fahim, Mohamed H Saad, Mai Badr
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Abstract

Background: Upper respiratory tract infections (URTIs) are one of the most frequent causes of childhood school leave and morbidity.

Aim: To study the present trend of medications' prescribing pattern utilized in URTIs among the pediatric population attending outpatient clinics in pediatric hospitals.

Methods: This analytical observational cross-sectional research was conducted in 200 children aged 1-10 years with URTIs attending the pediatric outpatient clinics in pediatric hospitals, one of which is an educational hospital, from July 2018 to August 2020.

Results: Most of the prescriptions in our study included antibiotics (116/58%). The most commonly prescribed antibiotic family was ampicillin/sulbactam or amoxicillin/clavulanic acid (53/26.5%), followed by first-generation cephalosporin (25/12.5%) and third-generation cephalosporin (20/10%). Macrolides and second-generation cephalosporins were prescribed less frequently, in 16 (8%) and 2 (1%) patients, respectively. Most of our study population (155/77.5%) was satisfied with their prescriptions, whereas the rest of the study population (45/22.5%) was unsatisfied.

Conclusion: Overprescription of antibiotics is a significant issue among clinicians in pediatric outpatient clinics. Stewardship of drugs, particularly antibiotics, is a must to prevent the development of drug resistance. Most cases of URTIs were treated in accordance with the existing national treatment guidelines.

儿科医院门诊患儿上呼吸道感染的用药模式
背景:上呼吸道感染(URTIs)是儿童辍学和发病的最常见原因之一。目的:了解儿科医院门诊儿童尿路感染用药模式的发展趋势。方法:对2018年7月至2020年8月在儿科医院(其中一家为教育医院)儿科门诊就诊的200名1-10岁尿路感染儿童进行分析性观察性横断面研究。结果:本组处方中抗生素占多数(116/58%)。最常使用的抗生素家族是氨苄西林/舒巴坦或阿莫西林/克拉维酸(53/26.5%),其次是第一代头孢菌素(25/12.5%)和第三代头孢菌素(20/10%)。大环内酯类药物和第二代头孢菌素的使用频率较低,分别为16例(8%)和2例(1%)。我们的大多数研究人群(155/77.5%)对他们的处方感到满意,而其余的研究人群(45/22.5%)不满意。结论:在儿科门诊,临床医生滥用抗生素是一个严重的问题。对药物,特别是抗生素进行管理,是防止耐药性发展的必要条件。大多数尿路感染病例是按照现有的国家治疗指南进行治疗的。
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