{"title":"Biological and Molecular Mechanisms of Wound Healing: Emerging Therapeutic Strategies and Future Directions.","authors":"Jun Xiong, Li Liu, Xuebing Zhang","doi":"10.1177/00031348251350983","DOIUrl":null,"url":null,"abstract":"<p><p>This review comprehensively examines the biological and molecular mechanisms underlying wound healing, focusing on inflammation, signaling pathways, and microenvironmental imbalances. By comparing traditional and emerging therapies, we highlight innovative approaches such as gene editing, stem cell therapy, and nanotechnology, which offer new perspectives for enhancing wound treatment outcomes. This study underscores the integration of modern medicine with traditional practices, providing a robust theoretical foundation for future clinical applications.</p>","PeriodicalId":7782,"journal":{"name":"American Surgeon","volume":" ","pages":"1966-1973"},"PeriodicalIF":0.9000,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Surgeon","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/00031348251350983","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/10 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0
Abstract
This review comprehensively examines the biological and molecular mechanisms underlying wound healing, focusing on inflammation, signaling pathways, and microenvironmental imbalances. By comparing traditional and emerging therapies, we highlight innovative approaches such as gene editing, stem cell therapy, and nanotechnology, which offer new perspectives for enhancing wound treatment outcomes. This study underscores the integration of modern medicine with traditional practices, providing a robust theoretical foundation for future clinical applications.
期刊介绍:
The American Surgeon is a monthly peer-reviewed publication published by the Southeastern Surgical Congress. Its area of concentration is clinical general surgery, as defined by the content areas of the American Board of Surgery: alimentary tract (including bariatric surgery), abdomen and its contents, breast, skin and soft tissue, endocrine system, solid organ transplantation, pediatric surgery, surgical critical care, surgical oncology (including head and neck surgery), trauma and emergency surgery, and vascular surgery.