Lung cancer screening in limited resource regions: the 3rd Brazilian Early Lung Cancer Trial (BRELT3/mobile ProPulmão).

IF 0.7 Q4 RESPIRATORY SYSTEM

Lung Cancer Management Pub Date : 2025-12-01 Epub Date: 2025-06-06 DOI:10.1080/17581966.2025.2513179

Ricardo Sales Dos Santos, Ricardo G Figueiredo, Juliana P Franceschini, Cesar Augusto de Araújo Neto, Almério de Souza Machado Júnior, Bruno Hochhegger, Mario Claudio Ghefter, Ulisses Amancio Pereira Neto, Petrucio Abrantes Sarmento, Igor Barbosa Ribeiro, Daniel Augusto Xavier Carvalho, Felipe S Passos, Caio Santos Holanda, Marcel Samuel Blech Hamaoui, Gustavo Borges da Silva Teles, Carolina Alves Neves, Helena Alves Costa Pereira, Jackline Pereira Leto, Adelmo de Souza Machado Neto, Audrey Cabral Ferreira de Oliveira, Fernando Nunes Galvão de Oliveira, Clarissa Mathias, César Garcia Machado, Josiane Dantas Viana Barbosa, Marine Oliveira Barbosa Santos, Crislaine Gomes da Silva, Mariana Moreira da Silva, Lila Teixeira de Araújo, Álvaro A Cruz

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引用次数: 0

Abstract

Aims: To describe tomographic findings in a high-risk lung cancer population in resource-limited Brazilian areas, quantify pulmonary nodules and lung cancer frequency, analyze challenges in lung cancer screening within the Brazilian public health system, assess lung function in individuals with moderate or severe emphysema, and evaluate the role of community health agents in recruiting high-risk populations.

Methods: This is a prospective, single-arm, longitudinal observational study involving individuals aged 50-80 years, current or former smokers with a smoking history of at least 20 pack-years, undergoing low-dose computed tomography (LDCT) with a 12-month follow-up. Screening results are classified according to Lung-RADS v2022 standards, with those rated as 3 or 4 undergoing further diagnostic assessments. The study aims to demonstrate the feasibility and effectiveness of lung cancer screening in socially vulnerable populations within resource-limited settings, providing essential insights to reduce mortality and improve health outcomes.

Conclusions: The findings will assist the development of policies on lung cancer screening in the public health system. The study's dissemination plan includes a website, social media, and participation in scientific conferences.

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资源有限地区的肺癌筛查：第三次巴西早期肺癌试验（BRELT3/移动propulm o）

目的：描述资源有限的巴西地区高风险肺癌人群的断层扫描结果，量化肺结节和肺癌频率，分析巴西公共卫生系统中肺癌筛查面临的挑战，评估中度或重度肺气肿患者的肺功能，并评估社区卫生机构在招募高风险人群中的作用。方法：这是一项前瞻性、单臂、纵向观察性研究，涉及年龄50-80岁、吸烟史至少20包年的当前或曾经吸烟者，接受低剂量计算机断层扫描（LDCT），随访12个月。筛查结果根据Lung-RADS v2022标准进行分类，评分为3或4的将进行进一步的诊断评估。该研究旨在证明在资源有限的情况下，在社会弱势群体中进行肺癌筛查的可行性和有效性，为降低死亡率和改善健康结果提供重要见解。结论：研究结果将有助于公共卫生系统中肺癌筛查政策的制定。该研究的传播计划包括一个网站、社交媒体和参加科学会议。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Lung Cancer Management RESPIRATORY SYSTEM-

CiteScore

2.30

自引率

0.00%

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