Unwanted pregnancies are associated with preterm birth, but not low birth weight.

IF 3.8 2区 医学 Q1 OBSTETRICS & GYNECOLOGY
Annie Dude, Jocelyn Wascher
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引用次数: 0

Abstract

Background: Prior studies indicate that unintended and unwanted pregnancies can be associated with poor obstetric outcomes.

Objective: This study examined whether an unintended or unwanted pregnancy was associated with a preterm delivery and with low birth weight.

Study design: We conducted a secondary analysis of the 2017-19 cycle of the National Survey of Family Growth, a nationally-representative population- based survey of reproductive-aged people identifying as female in the United States. The sample consisted of respondents who had at least one prior live birth. Respondents were asked whether their most recent pregnancy was wanted (either at that time or prior to that time), unintended (wanted, but too soon, or unwanted at any time), or unwanted (did not want to be pregnant at any time). The primary outcomes were preterm delivery, defined as a live birth prior to 37 weeks' gestation, and low birth weight, defined as a birthweight less than 2500 grams. We also examined early preterm delivery (defined as a live birth prior to 34 weeks' gestation) as a secondary outcome, as well as restricting the sample to term deliveries only to examine low birth weight. We used chi square and Wilcoxon rank sum analysis for bivariable comparisons and logistic regression for multivariable models.

Results: Our sample consisted of 3,299 unique deliveries, 35.4% of which resulted from unintended pregnancies and 16.9% of which resulted from unwanted pregnancies. Overall, 12.7% of respondents had any preterm delivery, including 11.3% of those with intended pregnancies, 15.4% of those with unintended pregnancies (p = 0.02), 11.9% of those with wanted pregnancies and 16.9% of those with unwanted pregnancies (p = 0.01). Of the overall sample, 3.7% had a preterm delivery prior to 34 weeks gestation, including 3.0% of those with an intended pregnancy, 4.9% of those with an unintended pregnancy (p = 0.10), 3.1% of those with wanted pregnancies, and 6.3% of those with unwanted pregnancies (p = 0.01). Unwanted pregnancies remained associated with preterm delivery and early preterm delivery after adjusting for confounders (adjusted odds ratio 1.42, 95% confidence interval 1.02 - 1.98 for any preterm delivery, adjusted odds ratio 1.84, 95% confidence interval 1.10 - 3.08 for early preterm delivery). In our sample, 8.0% of respondents had a low birth weight neonate, including 6.6% of those with an intended pregnancy, 10.5% of those with an unintended pregnancy (p = 0.02), 7.4% of those with wanted and 10.5% of those with unwanted pregnancies (p = 0.10). These results were insignificant among those with term deliveries and after adjusting for confounders.

Conclusion: Unwanted pregnancies are associated with an increased risk of preterm delivery, but not low birth weight.

意外怀孕与早产有关,但与低出生体重无关。
背景:先前的研究表明,意外怀孕和意外怀孕可能与不良的产科结局有关。目的:本研究探讨了意外怀孕是否与早产和低出生体重有关。研究设计:我们对2017-19年全国家庭增长调查周期进行了二次分析,这是一项具有全国代表性的基于人口的调查,调查对象是美国的育龄女性。样本包括至少有过一次活产的受访者。受访者被问及他们最近的怀孕是想要的(当时或之前),意外的(想要,但太早,或者任何时候都不想要),还是不想要的(任何时候都不想怀孕)。主要结局是早产(定义为妊娠37周前的活产)和低出生体重(定义为出生体重低于2500克)。我们还检查了早期早产(定义为妊娠34周之前的活产)作为次要结果,并将样本限制为足月分娩,仅用于检查低出生体重。我们对双变量比较使用卡方和Wilcoxon秩和分析,对多变量模型使用逻辑回归。结果:我们的样本包括3,299例独特分娩,其中35.4%是意外怀孕,16.9%是意外怀孕。总体而言,12.7%的受访者有早产,其中11.3%的人有妊娠,15.4%的人有意外妊娠(p = 0.02),11.9%的人有妊娠,16.9%的人有意外妊娠(p = 0.01)。在整个样本中,3.7%的人在妊娠34周之前早产,包括3.0%的预期妊娠,4.9%的意外妊娠(p = 0.10),3.1%的预期妊娠和6.3%的意外妊娠(p = 0.01)。调整混杂因素后,意外怀孕仍与早产和早期早产相关(任何早产的调整优势比1.42,95%可信区间1.02 - 1.98,早期早产的调整优势比1.84,95%可信区间1.10 - 3.08)。在我们的样本中,8.0%的受访者有低出生体重新生儿,其中包括6.6%的预期怀孕,10.5%的意外怀孕(p = 0.02),7.4%的希望怀孕和10.5%的意外怀孕(p = 0.10)。这些结果在足月分娩和调整混杂因素后不显著。结论:意外怀孕与早产风险增加有关,但与低出生体重无关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.40
自引率
3.20%
发文量
254
审稿时长
40 days
期刊介绍: The American Journal of Obstetrics and Gynecology (AJOG) is a highly esteemed publication with two companion titles. One of these is the American Journal of Obstetrics and Gynecology Maternal-Fetal Medicine (AJOG MFM), which is dedicated to the latest research in the field of maternal-fetal medicine, specifically concerning high-risk pregnancies. The journal encompasses a wide range of topics, including: Maternal Complications: It addresses significant studies that have the potential to change clinical practice regarding complications faced by pregnant women. Fetal Complications: The journal covers prenatal diagnosis, ultrasound, and genetic issues related to the fetus, providing insights into the management and care of fetal health. Prenatal Care: It discusses the best practices in prenatal care to ensure the health and well-being of both the mother and the unborn child. Intrapartum Care: It provides guidance on the care provided during the childbirth process, which is critical for the safety of both mother and baby. Postpartum Issues: The journal also tackles issues that arise after childbirth, focusing on the postpartum period and its implications for maternal health. AJOG MFM serves as a reliable forum for peer-reviewed research, with a preference for randomized trials and meta-analyses. The goal is to equip researchers and clinicians with the most current information and evidence-based strategies to effectively manage high-risk pregnancies and to provide the best possible care for mothers and their unborn children.
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