Roadmap: medical physics technologies in brachytherapy.

IF 3.3 3区 医学 Q2 ENGINEERING, BIOMEDICAL
William Youngjae Song, Michael Roumeliotis, Junghoon Lee, Aaron Fenster, Jessica Rodgers, Tiana Trumpour, Rachel Glicksman, Alejandro Berlin, Åsa Carlsson Tedgren, Javier Vijande, Luc Beaulieu, Björn Morén, Sandra Michelle Meyers, Alexandra Rink, Yin Gao, Benjamin Fahimian, Debarghya China, Kai Ding, Tarun Podder, Eric Carver, Mark J Rivard, Susan Richardson, Milan Grkovski, Moeen Meftahi, Ulysses Gardner, Rachit Kumar, Daniel Scanderbeg, Catheryn Yashar, Issam El Naqa, Akila N Viswanathan, Xun Jia
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Abstract

Brachytherapy is a crucial modality of radiotherapy for cancer, known for its effectiveness in delivering high doses of radiation directly to tumors while sparing surrounding healthy tissues. Despite its clinical importance, recent years have witnessed a concerning decline in its utilization, which negatively impacts patient outcomes. This decline is attributed to several factors, with the inherent complexity of brachytherapy, fair reimbursement policies, and high dexterity being significant barriers. There are silver linings, however, as growing number of applications are seen in continents such as Africa, as well as advances in medical physics technology offering promising solutions to these challenges. This roadmap paper aims to provide a comprehensive overview and preview of advancements in brachytherapy, as well as strategies to address key challenges in four critical areas: 'Imaging and Image Guidance,' 'Treatment Planning,' 'Treatment Delivery,' and 'Brachytherapy Outcomes.' We anticipate that these advances will enhance therapeutic efficacy, equipping clinicians worldwide with the tools needed to deliver state-of-the-art cancer treatments and fostering a promising future in oncology care.

路线图:近距离治疗中的医学物理技术。
近距离放射治疗是癌症放射治疗的一种重要方式,以其直接向肿瘤提供高剂量辐射而不影响周围健康组织的有效性而闻名。尽管其临床重要性,近年来其使用率有所下降,这对患者的预后产生了负面影响。这种下降归因于几个因素,近距离治疗的固有复杂性、公平的报销政策和高度灵活性是重大障碍。然而,也有一线希望,因为在非洲等大陆看到越来越多的应用,以及医学物理技术的进步为这些挑战提供了有希望的解决方案。这份路线图文件旨在提供近距离治疗进展的全面概述和预览,以及解决四个关键领域的关键挑战的策略:“成像和图像指导”,“治疗计划”,“治疗交付”和“近距离治疗结果”。我们预计这些进步将提高治疗效果,为全世界的临床医生提供最先进的癌症治疗所需的工具,并在肿瘤治疗方面创造一个充满希望的未来。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Physics in medicine and biology
Physics in medicine and biology 医学-工程:生物医学
CiteScore
6.50
自引率
14.30%
发文量
409
审稿时长
2 months
期刊介绍: The development and application of theoretical, computational and experimental physics to medicine, physiology and biology. Topics covered are: therapy physics (including ionizing and non-ionizing radiation); biomedical imaging (e.g. x-ray, magnetic resonance, ultrasound, optical and nuclear imaging); image-guided interventions; image reconstruction and analysis (including kinetic modelling); artificial intelligence in biomedical physics and analysis; nanoparticles in imaging and therapy; radiobiology; radiation protection and patient dose monitoring; radiation dosimetry
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