Rare Case of Pediatric Lower Limb Verrucous Venous Malformation: Treatment Approach and Considerations.

Eplasty Pub Date : 2025-01-21 eCollection Date: 2025-01-01
Annie Chen-Carrington, Adam Goodreau, Brian J Strife, Laurie Shinn, Jennifer Rhodes
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Abstract

Background: Verrucous venous malformation (VVM) is a rare, congenital, low-flow vascular anomaly composed of capillaries and veins in the dermis and subcutaneous tissues. Diagnosis is difficult because knowledge of cases is rare and typically identified with sonographic imaging and elevated GLUT-1. Treatment is mired by high rates of recurrence and residual pain, with further enlargement upon resection or injury. Current management strategies include a combination of laser therapy, surgery, cryotherapy, and topical steroids, each with varying rates of success.

Methods: The authors examine a case of confirmed VVM, which was initially treated with a candela pulsed dye laser and propranolol to no avail. A combination of surgical approaches were chosen.

Conclusions: We now look to topical sirolimus 1% as an adjunct for this patient with residual lesions. Questions remain as to the effectiveness, optimal dose, and duration of topical sirolimus and whether this combination of surgical and topical intervention will be effective in the treatment for VVM.

小儿下肢疣状静脉畸形1例:治疗方法及注意事项。
背景:疣状静脉畸形(VVM)是一种罕见的先天性低流量血管异常,由真皮和皮下组织的毛细血管和静脉组成。诊断是困难的,因为病例的知识是罕见的,通常通过超声成像和升高的GLUT-1来确定。治疗受困于高复发率和残余疼痛,切除或损伤后进一步扩大。目前的治疗策略包括激光治疗、手术、冷冻治疗和局部类固醇治疗,每种治疗方法的成功率各不相同。方法:作者检查了一例确诊的VVM,最初用坎德拉脉冲染料激光和心得安治疗无效。选择联合手术入路。结论:我们现在将1%局部西罗莫司作为残余病变患者的辅助治疗。关于局部西罗莫司的有效性、最佳剂量和持续时间,以及手术和局部干预联合治疗VVM是否有效的问题仍然存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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