INDIVIDUAL ARTICLE: Real-World Clinical Case Series Utilizing Acneceuticals as Monotherapy, Adjunctive, or Maintenance Therapy for Acne Vulgaris.

IF 1.5 4区 医学 Q3 DERMATOLOGY
Hilary Baldwin, Cheri Frey, Adelaide Hebert, Edward Ted Lain, Evan Rieder, Todd Schlesinger
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Abstract

Background: Acne vulgaris is a common, multifactorial inflammatory skin disease for which there are many pharmacologic and procedural interventions. Recent publications have stressed the importance of quality skin care containing non-prescription actives (acneceuticals) in the treatment of this chronic disorder. Acne therapy is made more complicated by the diversity of presentation that includes age, gender, race, underlying skin type, product adherence, lesion morphology, and severity.

Methods: A panel of 6 dermatologists with expertise in the treatment of acne met twice for consensus conferences in March and November 2024. Discussion included the generation of 13 common disease presentations, the identification of potential cases to illustrate the presentations, and the design of 2-month case studies utilizing acneceuticals. Panelists chose new or established patients in their care who fit into the predetermined categories, provided them with the agreed-upon acneceuticals, and followed them for 2 months.

Results: Ten cases were chosen to comprise the most common therapeutic crossroads where pharmacologic or procedural interventions were not providing satisfactory control. This case study series included patients who were medication-intolerant, failing internet cures, not fully responsive to their current regimen, adult female acne patients with concomitant aging concerns, those needing maintenance therapy, and patients with issues regarding access to care.

Conclusions: Acneceuticals were found to play an important role as monotherapy, adjunctive therapy, and maintenance therapy for acne patients. The 10 cases elucidated the ability of these over-the-counter (OTC) actives to improve patient care under several clinical scenarios. J Drugs Dermatol. 2025;24:6(Suppl 1):s3-14.

个别文章:现实世界的临床病例系列利用化妆品作为单一疗法,辅助,或维持治疗寻常痤疮。
背景:寻常痤疮是一种常见的多因素炎症性皮肤病,有许多药物和手术干预。最近的出版物强调了含有非处方活性成分(药物)的高质量皮肤护理在治疗这种慢性疾病中的重要性。痤疮的治疗因其表现的多样性而变得更加复杂,包括年龄、性别、种族、底层皮肤类型、产品粘附性、病变形态和严重程度。方法:由6名痤疮治疗专家组成的小组于2024年3月和11月召开了两次共识会议。讨论包括13种常见疾病表现的产生,潜在病例的识别来说明这些表现,以及利用药物进行为期2个月的病例研究的设计。小组成员选择符合预定类别的新患者或老患者,为他们提供商定的药物,并对他们进行2个月的随访。结果:选择10例,包括最常见的治疗十字路口,其中药物或程序干预不能提供满意的控制。本案例研究系列包括药物不耐受、网络治疗失败、对当前治疗方案没有完全反应的患者、伴随衰老的成年女性痤疮患者、需要维持治疗的患者以及难以获得护理的患者。结论:痤疮患者的单药治疗、辅助治疗和维持治疗均有重要作用。这10个病例阐明了这些非处方(OTC)活性药物在几种临床情况下改善患者护理的能力。皮肤医学杂志,2025;24:6(增刊1):53 -14。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.20
自引率
13.30%
发文量
289
审稿时长
3-6 weeks
期刊介绍: The Journal of Drugs in Dermatology (JDD) is a peer-reviewed publication indexed with MEDLINE®/PubMed® that was founded by the renowned Dr. Perry Robins MD. Founded in 2002, it offers one of the fastest routes to disseminate dermatologic information and is considered the fastest growing publication in dermatology. We present original articles, award-winning case reports, and timely features pertaining to new methods, techniques, drug therapy, and devices in dermatology that provide readers with peer reviewed content of the utmost quality. Our high standards of content are maintained through a balanced, peer-review process. Articles are reviewed by an International Editorial Board of over 160 renowned experts.
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