Measuring mobility in HIV research in sub-Saharan Africa: a scoping review

IF 4.6 1区 医学 Q2 IMMUNOLOGY
Aleya Khalifa, Sara Wallach, M. Kate Grabowski, Dustin T. Duncan, Fred Nalugoda, Quarraisha Abdool Karim, Barun Mathema
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引用次数: 0

Abstract

Introduction

Mobility—from overnight travel to permanent migration—can reduce service access and increase HIV risk, driving the epidemic in sub-Saharan Africa (SSA). This scoping review described mobility measures used in HIV research to identify gaps and guide research on mobility to strengthen HIV responses in SSA.

Methods

Literature from three databases (PubMed, Embase, Web of Science) were systematically screened to identify research articles examining relationships between mobility and individual-level HIV-related outcomes in SSA from 2014 through 2023. Key terms for mobility included “mobility,” “movement,” “migration” and “travel.” Measures were first extracted according to International Organization of Migration definitions of migration (a change in the place of usual residence) and travel (movement between geographies). Then, metrics used to categorize or quantify mobility were organized by the stage (origin, transit, destination, return) and dimension (spatial, temporal, socio-structural) of the movement captured. Measures were analysed within three research contexts: the HIV outcome(s) of interest, study population and local geographies. Outcomes included HIV acquisition, AIDS-related death, and indicators along the prevention, care and treatment cascade.

Results

We identified 69 studies after screening 5343 titles/abstracts and 200 full texts for eligibility. Studies included research from 16 countries, mostly representing general adult populations in eastern and southern Africa. Most studies measured migration (51) versus travel (21) and examined relationships with HIV prevalent infection (29) or care and treatment indicators (44) compared to other epidemiological and programmatic outcomes. Studies employed a range of metrics, mostly of the duration of stay at the destination (28), the number of mobility events (12) or the geographic boundaries across which individuals moved (14). Socio-structural dimensions like the motivation for movement were measured less often. Only 15 studies examined more than one dimension.

Discussion

Mobility measures varied widely and were inconsistently studied across research contexts. Future studies should fill evidence gaps, standardize reporting and develop multidimensional mobility measures tailored to local settings and HIV outcomes.

Conclusions

People on the move are a vast and diverse group, yet they are often labelled as a monolith. Improved measures can disentangle how different forms of mobility relate to HIV, generating actionable evidence to enhance HIV programming for ending the epidemic.

衡量撒哈拉以南非洲艾滋病毒研究的流动性:范围审查
流动——从过夜旅行到永久迁移——会减少获得服务的机会,增加艾滋病毒的风险,推动撒哈拉以南非洲(SSA)的流行。这一范围综述描述了艾滋病研究中使用的流动性措施,以确定差距并指导流动性研究,以加强SSA的艾滋病毒应对。方法系统筛选来自三个数据库(PubMed, Embase, Web of Science)的文献,以确定2014年至2023年SSA中流动性与个人水平hiv相关结局之间关系的研究文章。流动性的关键术语包括“流动性”、“运动”、“迁移”和“旅行”。首先根据国际移徙组织关于移徙(常住地点的改变)和旅行(不同地区之间的移动)的定义提取措施。然后,根据所捕获的运动的阶段(起源、中转、目的地、返回)和维度(空间、时间、社会结构)来组织用于分类或量化流动性的指标。在三个研究背景下对措施进行了分析:感兴趣的艾滋病毒结果、研究人口和当地地理位置。结果包括艾滋病毒感染、艾滋病相关死亡以及预防、护理和治疗级联的指标。结果在筛选5343篇标题/摘要和200篇全文后,我们确定了69篇研究。研究包括来自16个国家的研究,主要代表非洲东部和南部的普通成年人。大多数研究衡量了移民(51)与旅行(21)的关系,并与其他流行病学和规划结果相比,检查了与艾滋病毒流行感染(29)或护理和治疗指标(44)的关系。研究采用了一系列指标,主要是在目的地停留的时间(28),流动事件的数量(12)或个人移动的地理边界(14)。运动动机等社会结构维度的测量频率较低。只有15项研究考察了不止一个维度。流动性措施差异很大,在不同的研究背景下研究的不一致。未来的研究应该填补证据空白,使报告标准化,并制定适合当地环境和艾滋病毒结果的多维流动性措施。流动的人是一个庞大而多样的群体,然而他们经常被贴上巨石的标签。改进的措施可以理清不同形式的流动与艾滋病毒之间的关系,产生可操作的证据,以加强艾滋病毒方案编制,以结束这一流行病。
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来源期刊
Journal of the International AIDS Society
Journal of the International AIDS Society IMMUNOLOGY-INFECTIOUS DISEASES
CiteScore
8.60
自引率
10.00%
发文量
186
审稿时长
>12 weeks
期刊介绍: The Journal of the International AIDS Society (JIAS) is a peer-reviewed and Open Access journal for the generation and dissemination of evidence from a wide range of disciplines: basic and biomedical sciences; behavioural sciences; epidemiology; clinical sciences; health economics and health policy; operations research and implementation sciences; and social sciences and humanities. Submission of HIV research carried out in low- and middle-income countries is strongly encouraged.
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