Craig R Louer, Jacquelyn S Pennings, Maty Petcharaporn, Arun R Hariharan, John S Vorhies, Michael P Kelly, Suken A Shah, Peter O Newton, Burt Yaszay, Harms Study Group
{"title":"Anterior release is not needed to restore kyphosis in moderate AIS with hypokyphosis.","authors":"Craig R Louer, Jacquelyn S Pennings, Maty Petcharaporn, Arun R Hariharan, John S Vorhies, Michael P Kelly, Suken A Shah, Peter O Newton, Burt Yaszay, Harms Study Group","doi":"10.1007/s43390-025-01119-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to evaluate if AR offers improved 3D kyphosis restoration during PSF for hypokyphosis in moderate AIS (< 70° coronal cobb), where the decision for AR is likely driven by sagittal concerns.</p><p><strong>Methods: </strong>A multicenter pediatric spine registry was queried for hypokyphotic (< 10°) Lenke 1-4 AIS patients aged < 20 years with > 2-year surgical follow-up. Coronal curves were limited to < 70°. A linear mixed model was created to predict 2-year 3D kyphosis by treatment and pre-op 3D kyphosis, while controlling for age, sex, thoracic coronal deformity and flexibility, osteotomy use, implant characteristics, surgery recency, and surgeon.</p><p><strong>Results: </strong>1384 patients were included with 53 (3.8%) undergoing PSF + AR. Mean preop 3D kyphosis was similar between PSF and PSF + AR groups (- 3.7° vs. - 0.5°; p = 0.08). PSF-AR had similar 2-year 3D kyphosis (23.0° [95% CI 20.5-25.4°] vs. 23.3° [22.9-23.6°]) and correction (26.7° [23.3-29.9°] vs. 23.7° [23.3-24.2°]) compared to PSF. When controlling for covariates, the models demonstrated no difference between approach (p = 0.058) or interaction of approach and preop 3D kyphosis (p = 0.31). Post-hoc power analysis showed an adequate sample size to detect a difference of 5° between approaches. PSF + AR had longer surgical times (324 vs. 266 min, p < 0.001) though no significant increase in overall complications (17% vs. 12.4%) compared to PSF alone.</p><p><strong>Conclusion: </strong>In AIS patients with coronal curve < 70° and 3D hypokyphosis of 10 to - 40°, treatment with PSF + AR did not improve 2-year sagittal correction more than PSF alone. Surgeon identity and surgery recency influenced post-operative kyphosis more than any other patient or surgical factor.</p>","PeriodicalId":21796,"journal":{"name":"Spine deformity","volume":" ","pages":"1465-1475"},"PeriodicalIF":1.8000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12402032/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spine deformity","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s43390-025-01119-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/3 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: The purpose of this study is to evaluate if AR offers improved 3D kyphosis restoration during PSF for hypokyphosis in moderate AIS (< 70° coronal cobb), where the decision for AR is likely driven by sagittal concerns.
Methods: A multicenter pediatric spine registry was queried for hypokyphotic (< 10°) Lenke 1-4 AIS patients aged < 20 years with > 2-year surgical follow-up. Coronal curves were limited to < 70°. A linear mixed model was created to predict 2-year 3D kyphosis by treatment and pre-op 3D kyphosis, while controlling for age, sex, thoracic coronal deformity and flexibility, osteotomy use, implant characteristics, surgery recency, and surgeon.
Results: 1384 patients were included with 53 (3.8%) undergoing PSF + AR. Mean preop 3D kyphosis was similar between PSF and PSF + AR groups (- 3.7° vs. - 0.5°; p = 0.08). PSF-AR had similar 2-year 3D kyphosis (23.0° [95% CI 20.5-25.4°] vs. 23.3° [22.9-23.6°]) and correction (26.7° [23.3-29.9°] vs. 23.7° [23.3-24.2°]) compared to PSF. When controlling for covariates, the models demonstrated no difference between approach (p = 0.058) or interaction of approach and preop 3D kyphosis (p = 0.31). Post-hoc power analysis showed an adequate sample size to detect a difference of 5° between approaches. PSF + AR had longer surgical times (324 vs. 266 min, p < 0.001) though no significant increase in overall complications (17% vs. 12.4%) compared to PSF alone.
Conclusion: In AIS patients with coronal curve < 70° and 3D hypokyphosis of 10 to - 40°, treatment with PSF + AR did not improve 2-year sagittal correction more than PSF alone. Surgeon identity and surgery recency influenced post-operative kyphosis more than any other patient or surgical factor.
期刊介绍:
Spine Deformity the official journal of the?Scoliosis Research Society is a peer-refereed publication to disseminate knowledge on basic science and clinical research into the?etiology?biomechanics?treatment?methods and outcomes of all types of?spinal deformities. The international members of the Editorial Board provide a worldwide perspective for the journal's area of interest.The?journal?will enhance the mission of the Society which is to foster the optimal care of all patients with?spine?deformities worldwide. Articles published in?Spine Deformity?are Medline indexed in PubMed.? The journal publishes original articles in the form of clinical and basic research. Spine Deformity will only publish studies that have institutional review board (IRB) or similar ethics committee approval for human and animal studies and have strictly observed these guidelines. The minimum follow-up period for follow-up clinical studies is 24 months.