A Birdcage Volume Transmit Coil and 8 Channel Receive Array for Marmoset Brain Imaging at 7T.

IF 4.5 2区医学 Q2 ENGINEERING, BIOMEDICAL

IEEE Transactions on Biomedical Engineering Pub Date : 2025-06-02 DOI:10.1109/TBME.2025.3576064

Pedram Yazdanbakhsh, Maeva Gacoin, Marcus J Couch, Tyler Cook, Ilana R Leppert, David A Rudko, Justine Clery

{"title":"A Birdcage Volume Transmit Coil and 8 Channel Receive Array for Marmoset Brain Imaging at 7T.","authors":"Pedram Yazdanbakhsh, Maeva Gacoin, Marcus J Couch, Tyler Cook, Ilana R Leppert, David A Rudko, Justine Clery","doi":"10.1109/TBME.2025.3576064","DOIUrl":null,"url":null,"abstract":"Objective: To design and fabricate a band-pass birdcage volume resonator and eight channel, conformal receive array coil for MRI of both awake and anesthetized marmoset brain at 7T. The coil is compatible with a whole body 7T clinical MRI scanner running in single channel transmit (sTx) mode.Methods: The marmoset head coil included a shielded, band-pass birdcage transmit coil with 24 legs, as well as 8 overlapped receive elements. Electromagnetic (EM) field simulation was performed for the 24 leg band pass birdcage Tx coil to calculate the B1 + efficiency. The efficacy of both transmit and receive coil designs were evaluated by measuring standard coil performance metrics. This was done while imaging a marmoset head phantom, as well as by acquiring in vivo, anesthetized and awake marmoset images.Results: The transmit coil along with the optimized receive array produced high resolution (0.8 mm isotropic for EPI images; 0.36 mm isotropic for structural images) and high SNR (between 50 and 80) images of the marmoset brain. The simulated B1 + efficiency of the birdcage at the center of the phantom was 2.6 μT/sqrt (W).Conclusion and significance: A shielded, band-pass birdcage transmit coil was designed and fabricated for marmoset brain imaging at 7T. An 8-channel receive array consisting of eight overlapped loops, covering the whole brain of the marmoset, was also constructed and applied for signal reception. The system successfully allowed scanning of both young and older marmosets. It is well-suited for longitudinal studies of marmoset brain structure. The coil advantageously allows the study of neurodevelopment and primate brain function.","PeriodicalId":13245,"journal":{"name":"IEEE Transactions on Biomedical Engineering","volume":"PP ","pages":""},"PeriodicalIF":4.5000,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Transactions on Biomedical Engineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1109/TBME.2025.3576064","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: To design and fabricate a band-pass birdcage volume resonator and eight channel, conformal receive array coil for MRI of both awake and anesthetized marmoset brain at 7T. The coil is compatible with a whole body 7T clinical MRI scanner running in single channel transmit (sTx) mode.

Methods: The marmoset head coil included a shielded, band-pass birdcage transmit coil with 24 legs, as well as 8 overlapped receive elements. Electromagnetic (EM) field simulation was performed for the 24 leg band pass birdcage Tx coil to calculate the B1 + efficiency. The efficacy of both transmit and receive coil designs were evaluated by measuring standard coil performance metrics. This was done while imaging a marmoset head phantom, as well as by acquiring in vivo, anesthetized and awake marmoset images.

Results: The transmit coil along with the optimized receive array produced high resolution (0.8 mm isotropic for EPI images; 0.36 mm isotropic for structural images) and high SNR (between 50 and 80) images of the marmoset brain. The simulated B1 + efficiency of the birdcage at the center of the phantom was 2.6 μT/sqrt (W).

Conclusion and significance: A shielded, band-pass birdcage transmit coil was designed and fabricated for marmoset brain imaging at 7T. An 8-channel receive array consisting of eight overlapped loops, covering the whole brain of the marmoset, was also constructed and applied for signal reception. The system successfully allowed scanning of both young and older marmosets. It is well-suited for longitudinal studies of marmoset brain structure. The coil advantageously allows the study of neurodevelopment and primate brain function.

查看原文本刊更多论文

笼形体积发射线圈和8通道接收阵列用于7T狨猴脑成像。

目的：设计和制作一种带通鸟笼式容积谐振器和八通道适形接收阵列线圈，用于7T时清醒和麻醉的狨猴脑MRI。该线圈与以单通道传输（sTx）模式运行的全身7T临床MRI扫描仪兼容。方法：绒猴头线圈包括一个屏蔽带通鸟笼式24腿传输线圈和8个重叠接收元件。对24腿带通鸟笼Tx线圈进行电磁场仿真，计算B1 +效率。通过测量标准线圈性能指标来评估发射和接收线圈设计的有效性。这是在对狨猴头部幻影成像的同时完成的，也可以通过获得活体、麻醉和清醒的狨猴图像来完成。结果：发射线圈与优化后的接收阵列可获得高分辨率（各向同性0.8 mm）的EPI图像；结构图像的各向同性为0.36 mm)和高信噪比（在50到80之间）的狨猴大脑图像。模拟模型中心鸟笼的B1 +效率为2.6 μT/sqrt (W)。结论与意义：设计并制作了一种屏蔽带通鸟笼式传输线圈，用于狨猴7T脑成像。构建了覆盖狨猴全脑的8通道信号接收阵列，并将其应用于信号接收。该系统成功地扫描了年幼和年长的狨猴。它非常适合于狨猴大脑结构的纵向研究。线圈有利于神经发育和灵长类脑功能的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

IEEE Transactions on Biomedical Engineering 工程技术-工程：生物医学

CiteScore

9.40

自引率

4.30%

发文量

880

审稿时长

2.5 months

期刊介绍： IEEE Transactions on Biomedical Engineering contains basic and applied papers dealing with biomedical engineering. Papers range from engineering development in methods and techniques with biomedical applications to experimental and clinical investigations with engineering contributions.