Cangtuo Li, Qi Qi, Wansong Li, Xuechao Zhang, Lei Li, Jie Deng, Quanle Han, Shouling Wu, Kangbo Li
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引用次数: 0
Abstract
Background: The association between the triglyceride-glucose (TyG) index and the occurrence of major adverse cardiovascular and cerebrovascular events (MACCEs) in individuals without diabetes has not been clearly established.
Aims: To investigate the potential of the TyG index to predict MACCEs in a non-diabetic population.
Study design: Prospective cohort study.
Methods: This study analyzed data from 88,946 participants without diabetes, who were divided into four groups based on their TyG index values. The primary outcome was the occurrence of MACCEs, defined as myocardial infarction (MI) or stroke. Multivariable Cox proportional hazards regression models were used to assess the association between the TyG index and MACCEs.
Results: Participants in the higher TyG index quartiles exhibited a greater risk of MACCEs. Moreover, a significant interaction between the TyG index and sex was identified, with a stronger association observed in women than in men. A significant interaction was also found between the TyG index and age in relation to MI risk, indicating a stronger associations in individuals younger than 60 compared to those aged 60 or older.
Conclusion: The TyG index may serve as a useful prognostic marker for MACCEs among individuals without diabetes.
期刊介绍：
The Balkan Medical Journal (Balkan Med J) is a peer-reviewed open-access international journal that publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports and clinical images, invited reviews, editorials, letters, comments and letters to the Editor including reports on publication and research ethics. The journal is the official scientific publication of the Trakya University Faculty of Medicine, Edirne, Turkey and is printed six times a year, in January, March, May, July, September and November. The language of the journal is English.
The journal is based on independent and unbiased double-blinded peer-reviewed principles. Only unpublished papers that are not under review for publication elsewhere can be submitted. Balkan Medical Journal does not accept multiple submission and duplicate submission even though the previous one was published in a different language. The authors are responsible for the scientific content of the material to be published. The Balkan Medical Journal reserves the right to request any research materials on which the paper is based.
The Balkan Medical Journal encourages and enables academicians, researchers, specialists and primary care physicians of Balkan countries to publish their valuable research in all branches of medicine. The primary aim of the journal is to publish original articles with high scientific and ethical quality and serve as a good example of medical publications in the Balkans as well as in the World.
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