Clinical Characteristics and Factors Influencing the Outcomes of In-Hospital Cardiac Arrest Patients: A Retrospective Observational Study.

IF 0.5 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Kardiologiya Pub Date : 2025-06-02 DOI:10.18087/cardio.2025.5.n2719

Yuliu Xu, Jiang Hao, Xiaomin Mei, Yan Zhen

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引用次数: 0

Abstract

Objective: Analyze the clinical characteristics and resuscitation outcomes of patients with in-hospital cardiac arrest (IHCA) and explore the factors affecting the success rate of cardiopulmonary resuscitation in IHCA patients.

Material and methods: A retrospective observational study was conducted. Patients who received resuscitative treatment for IHCA between September 2022 and December 2023 were evaluated. Clinical data and prognostic information were collected and analyzed, including age, gender, underlying diseases, time of cardiac arrest, cause of cardiac arrest, presence of shockable rhythm, application of defibrillation, duration of CPR (>30 min), presence of endotracheal intubation, cumulative dose of adrenaline, and resuscitation outcomes (return of spontaneous circulation, survival to discharge).

Results: A total of 323 IHCA patients were included in this study. After CPR treatment, 246 had return of spontaneous circulation (ROSC), with 90 surviving to discharge. Coronary artery disease, shockable initial rhythm, presence of a shockable rhythm during resuscitation, defibrillation, and absence of emergency endotracheal intubation differed statistically between the ROSC and non-ROSC groups (univariate analysis, p < 0.001) Age was a statistically significant determinant of whether patients survived to discharge (p < 0.05). Multivariate logistic regression analysis showed that CPR duration ≥ 30 min was an independent risk factor for ROSC, while younger age, application of emergency endotracheal intubation, and lower cumulative dose of adrenaline were independent protective factors for ROSC (p < 0.05).

Conclusion: Age lower than 60 years old, application of defibrillation, and emergency endotracheal intubation are positively associated with increased likelihood of ROSC. Age is an independent risk factor negatively related to survival after discharge. Clinicians should pay close attention to these factors to improve the outcomes of cardiopulmonary resuscitation patients.

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住院心脏骤停患者的临床特征及影响预后的因素：一项回顾性观察研究

目的：分析院内心脏骤停（IHCA）患者的临床特点及复苏结局，探讨影响IHCA患者心肺复苏成功率的因素。材料和方法：采用回顾性观察性研究。对2022年9月至2023年12月期间接受IHCA复苏治疗的患者进行评估。收集和分析临床数据和预后信息，包括年龄、性别、基础疾病、心脏骤停时间、心脏骤停原因、是否存在震荡性心律、是否应用除颤、心肺复苏术持续时间（30分钟）、是否使用气管插管、肾上腺素累积剂量和复苏结果（自然循环恢复、存活至出院）。结果：本研究共纳入323例IHCA患者。经心肺复苏术治疗，246例恢复自然循环（ROSC）， 90例存活至出院。冠状动脉疾病、休克初始节律、复苏过程中出现休克节律、除颤和没有紧急气管插管在ROSC组和非ROSC组之间有统计学差异(单变量分析，p <；0.001)年龄是患者是否存活至出院的有统计学意义的决定因素(p <；0.05)。多因素logistic回归分析显示，CPR持续时间≥30 min是ROSC的独立危险因素，而年龄较小、应用紧急气管插管、肾上腺素累积剂量较低是ROSC的独立保护因素(p <；0.05)。结论：年龄小于60岁、应用除颤和急诊气管插管与ROSC的可能性增加呈正相关。年龄是与出院后生存负相关的独立危险因素。临床医生应密切关注这些因素，以改善心肺复苏患者的预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Kardiologiya 医学-心血管系统

CiteScore

1.70

自引率

20.00%

发文量

审稿时长

3-8 weeks

期刊介绍： “Kardiologiya” (Cardiology) is a monthly scientific, peer-reviewed journal committed to both basic cardiovascular medicine and practical aspects of cardiology. As the leader in its field, “Kardiologiya” provides original coverage of recent progress in cardiovascular medicine. We publish state-of-the-art articles integrating clinical and research activities in the fields of basic cardiovascular science and clinical cardiology, with a focus on emerging issues in cardiovascular disease. Our target audience spans a diversity of health care professionals and medical researchers working in cardiovascular medicine and related fields. The principal language of the Journal is Russian, an additional language – English (title, authors’ information, abstract, keywords). “Kardiologiya” is a peer-reviewed scientific journal. All articles are reviewed by scientists, who gained high international prestige in cardiovascular science and clinical cardiology. The Journal is currently cited and indexed in major Abstracting & Indexing databases: Web of Science, Medline and Scopus. The Journal''s primary objectives Contribute to raising the professional level of medical researchers, physicians and academic teachers. Present the results of current research and clinical observations, explore the effectiveness of drug and non-drug treatments of heart disease, inform about new diagnostic techniques; discuss current trends and new advancements in clinical cardiology, contribute to continuing medical education, inform readers about results of Russian and international scientific forums; Further improve the general quality of reviewing and editing of manuscripts submitted for publication; Provide the widest possible dissemination of the published articles, among the global scientific community; Extend distribution and indexing of scientific publications in major Abstracting & Indexing databases.