Jeah Jung, Caroline Carlin, Roger Feldman, Ge Song, Aaron Mitchell
{"title":"Use of Low-Value Cancer Treatments in Medicare Advantage Versus Traditional Medicare.","authors":"Jeah Jung, Caroline Carlin, Roger Feldman, Ge Song, Aaron Mitchell","doi":"10.1200/JCO-24-01907","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Medicare Advantage (MA) provides beneficiaries an option to receive Medicare benefits from private plans. Although MA covers over half of the Medicare population, limited information exists about how utilization of cancer treatments in MA differs from traditional Medicare (TM). We compared use of low-value cancer treatments between MA and TM and analyzed variation in use of low-value cancer treatments across large MA insurers.</p><p><strong>Methods: </strong>Using national Medicare data, we performed retrospective analyses of beneficiaries who had a new cancer diagnosis between 2016 and 2021 and who were at risk of receiving a low-value treatment: granulocyte-colony stimulating factors (GCSFs) for patients receiving low-risk chemotherapy, denosumab for castration-sensitive prostate cancer (CSPC), nab-paclitaxel instead of paclitaxel for breast or lung cancers, adding bevacizumab to carboplatin plus paclitaxel for ovarian cancer, and branded drugs or biologics for which generic or biosimilar versions existed.</p><p><strong>Results: </strong>Use of any low-value cancer treatment was 1.7 percentage points lower in MA than in TM (34.2% <i>v</i> 35.9%; <i>P</i> < .001). MA had lower utilization rates than TM for GCSF among patients receiving low-risk chemotherapy (7.3% <i>v</i> 8.9%; <i>P</i> < .001), denosumab for CSPC (26.4% <i>v</i> 33.1%; <i>P</i> < .001), nab-paclitaxel for breast or lung cancer (7.9% <i>v</i> 8.7%; <i>P</i> < .001), addition of bevacizumab for ovarian cancer (8.3% <i>v</i> 10.5%; <i>P</i> < .001), and biologics with biosimilar alternatives (66.8% <i>v</i> 68.5%; <i>P</i> < .001). Use of branded drugs did not significantly differ between MA and TM. The differences in use of low-value cancer treatments from TM varied moderately across large MA insurers.</p><p><strong>Conclusion: </strong>MA has lower use of low-value cancer treatments than TM, with varying degrees across large MA insurers. Efforts are needed to identify effective strategies to reduce use of low-value cancer treatments.</p>","PeriodicalId":15384,"journal":{"name":"Journal of Clinical Oncology","volume":" ","pages":"JCO2401907"},"PeriodicalIF":42.1000,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1200/JCO-24-01907","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: Medicare Advantage (MA) provides beneficiaries an option to receive Medicare benefits from private plans. Although MA covers over half of the Medicare population, limited information exists about how utilization of cancer treatments in MA differs from traditional Medicare (TM). We compared use of low-value cancer treatments between MA and TM and analyzed variation in use of low-value cancer treatments across large MA insurers.
Methods: Using national Medicare data, we performed retrospective analyses of beneficiaries who had a new cancer diagnosis between 2016 and 2021 and who were at risk of receiving a low-value treatment: granulocyte-colony stimulating factors (GCSFs) for patients receiving low-risk chemotherapy, denosumab for castration-sensitive prostate cancer (CSPC), nab-paclitaxel instead of paclitaxel for breast or lung cancers, adding bevacizumab to carboplatin plus paclitaxel for ovarian cancer, and branded drugs or biologics for which generic or biosimilar versions existed.
Results: Use of any low-value cancer treatment was 1.7 percentage points lower in MA than in TM (34.2% v 35.9%; P < .001). MA had lower utilization rates than TM for GCSF among patients receiving low-risk chemotherapy (7.3% v 8.9%; P < .001), denosumab for CSPC (26.4% v 33.1%; P < .001), nab-paclitaxel for breast or lung cancer (7.9% v 8.7%; P < .001), addition of bevacizumab for ovarian cancer (8.3% v 10.5%; P < .001), and biologics with biosimilar alternatives (66.8% v 68.5%; P < .001). Use of branded drugs did not significantly differ between MA and TM. The differences in use of low-value cancer treatments from TM varied moderately across large MA insurers.
Conclusion: MA has lower use of low-value cancer treatments than TM, with varying degrees across large MA insurers. Efforts are needed to identify effective strategies to reduce use of low-value cancer treatments.
目的:医疗保险优势(MA)为受益人提供从私人计划中获得医疗保险福利的选择。尽管MA覆盖了医疗保险人口的一半以上,但关于MA中癌症治疗的利用与传统医疗保险(TM)有何不同的信息有限。我们比较了MA和TM之间低价值癌症治疗的使用情况,并分析了大型MA保险公司使用低价值癌症治疗的差异。方法:使用国家医疗保险数据,我们对2016年至2021年间新发癌症诊断并有接受低价值治疗风险的受益人进行了回顾性分析:用于接受低风险化疗的患者的粒细胞集落刺激因子(gcsf),用于阉割敏感性前列腺癌(CSPC)的地诺单抗,用于乳腺癌或肺癌的nab-紫杉醇代替紫杉醇,用于卵巢癌的在卡铂加紫杉醇基础上添加贝伐珠单抗,以及存在仿制药或生物仿制药的品牌药物或生物制剂。结果:MA患者使用任何低价值癌症治疗的比例比TM患者低1.7个百分点(34.2% vs 35.9%;P < 0.001)。在接受低风险化疗的患者中,MA的GCSF使用率低于TM (7.3% vs 8.9%;P < .001), denosumab用于CSPC (26.4% vs 33.1%;P < 0.001), nab-紫杉醇用于乳腺癌或肺癌(7.9% vs 8.7%;P < 0.001),加用贝伐单抗治疗卵巢癌(8.3% vs 10.5%;P < .001),以及具有生物类似药替代品的生物制剂(66.8% vs 68.5%;P < 0.001)。品牌药的使用在MA和TM之间没有显著差异。在使用TM低价值癌症治疗方面的差异在大型MA保险公司之间存在适度差异。结论:在大型保险公司中,MA低价值癌症治疗的使用率低于TM。需要努力确定有效的策略,以减少低价值癌症治疗的使用。
期刊介绍:
The Journal of Clinical Oncology serves its readers as the single most credible, authoritative resource for disseminating significant clinical oncology research. In print and in electronic format, JCO strives to publish the highest quality articles dedicated to clinical research. Original Reports remain the focus of JCO, but this scientific communication is enhanced by appropriately selected Editorials, Commentaries, Reviews, and other work that relate to the care of patients with cancer.