Julien A M Vos, Laura A M Duineveld, Thijs Wieldraaijer, Jan Wind, Wim B Busschers, Edanur Sert, Irma M Verdonck-de Leeuw, Henk C P M van Weert, Kristel M van Asselt
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引用次数: 0
Abstract
The randomized controlled I CARE (Improving Care After colon canceR treatment in the Netherlands) trial evaluated the impact of general practitioner-led vs surgeon-led survivorship care on quality of life (QoL) in colorectal cancer survivors, alongside the effect of the eHealth application Oncokompas. The trial was conducted in 8 hospitals and 225 general practices across the Netherlands, including 303 patients who underwent surgery for stage I-III colon cancer or rectosigmoid carcinoma. Patients were randomly assigned into 4 groups: surgeon-led care, surgeon-led care with Oncokompas, general practitioner-led care, and general practitioner-led care with Oncokompas. QoL was assessed at multiple time points over 60 months. At 60 months, no clinically relevant differences in QoL were found between general practitioner-led and surgeon-led care (difference in summary score = -0.5, 95% CI = -1.6 to 0.5) or with Oncokompas (difference = 0.8, 95% CI = 0.0 to 1.6). In conclusion, neither general practitioner involvement nor access to Oncokompas led to clinically relevant improvements in long-term QoL. Survivorship care can be tailored to preferences. Netherlands Trial Register; NTR4860.
随机对照I CARE试验评估了全科医生（GP）主导与外科医生主导的生存护理对结直肠癌幸存者生活质量（QoL）的影响，以及电子健康应用程序Oncokompas的效果。该试验在荷兰的8家医院和225家全科诊所进行，其中包括303名因I-III期结肠癌或直肠乙状结肠癌接受手术的患者。患者被随机分为四组：外科医生主导的治疗、外科医生主导的治疗合并Oncokompas、gp主导的治疗和gp主导的治疗合并Oncokompas。在60个月内的多个时间点评估生活质量。在60个月时，gp主导和外科主导的护理之间的生活质量没有临床意义的差异（总评分差异：-0.5 [95% CI -1.6至0.5]）或Oncokompas（差异：0.8[0.0至1.6]）。总之，全科医生介入和使用Oncokompas都不能显著改善长期生活质量。遗属护理可以根据个人喜好进行调整。荷兰审判登记册；NTR4860。
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