How does internal fixation compared with arthroplasty affect quality of life for patients who have suffered femoral neck fractures?

Zafar Ahmad, Daniel Axelrod, Marianne Comeau-Gauthier, Sofia Bzovsky, Rudolf W Poolman, Frede Frihagen, Mohit Bhandari, Marc Swiontkowski, Sheila Sprague, Emil Schemitsch
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引用次数: 0

Abstract

Objectives: To evaluate functional outcomes amongst femoral neck fracture trial participants who did not undergo reoperation.

Design: Secondary analysis of 2 randomized controlled trials.

Setting: Ninety hospitals in 5 continents.

Participants: Patients aged 50 years or older with a femoral neck fracture.

Intervention: Arthroplasty, including total hip arthroplasty and hemiarthroplasty, or internal fixation, including sliding hip screw or multiple cancellous screws.

Main outcome measurement: The Western Ontario and McMaster University Arthritis Index (WOMAC) and 12-item Short Form Health Survey (SF-12) physical component summary (PCS).

Results: Data from 716 arthroplasty patients and 549 internal fixation patients were included in our propensity score weighting model. Internal fixation patients had higher WOMAC stiffness scores (leading to poorer function) at 24 months postoperatively compared with total hip arthroplasty patients (adjusted mean difference [AMD] 0.42 points, 99% confidence interval [CI] 0.09-0.75; P < 0.001) and hemiarthroplasty patients (AMD 0.39 points, 99% CI 0.04-0.74; P = 0.004). However, this statistically significant difference did not reach the 7-point threshold for a minimal clinically important difference. No statistically significant differences were found in the other WOMAC scales, nor with the SF-12 PCS. In participants aged 70 years or younger, no difference was found in any of the functional outcomes at 24 months.

Conclusion: While stiffness is worse following internal fixation, our results show similar functional outcomes in femoral neck fracture patients undergoing modern methods of internal fixation versus arthroplasty. These results, however, may not be applicable to a younger, more active hip fracture population.

Level of evidence: Prognostic Level II.

股骨颈骨折患者的内固定与关节置换术相比如何影响患者的生活质量?
目的:评价未再手术的股骨颈骨折试验参与者的功能结局。设计:2个随机对照试验的二次分析。环境:分布在五大洲的90家医院。参与者:年龄在50岁及以上的股骨颈骨折患者。干预:关节置换术,包括全髋关节置换术和半髋关节置换术,或内固定,包括滑动髋关节螺钉或多个松质螺钉。主要结果测量:西安大略省和麦克马斯特大学关节炎指数(WOMAC)和12项简短健康调查(SF-12)身体成分总结(PCS)。结果:来自716例关节置换术患者和549例内固定患者的数据被纳入我们的倾向评分加权模型。与全髋关节置换术患者相比,内固定患者术后24个月WOMAC刚度评分较高(导致功能较差)(调整后平均差[AMD] 0.42分,99%可信区间[CI] 0.09-0.75;P < 0.001)和半关节置换术患者(AMD 0.39分,99% CI 0.04-0.74;P = 0.004)。然而,这一具有统计学意义的差异并没有达到7分的临界值。其他WOMAC量表和SF-12 PCS均无统计学差异。在70岁或以下的参与者中,在24个月时,没有发现任何功能结果的差异。结论:虽然内固定后僵硬程度更差,但我们的研究结果显示,股骨颈骨折患者采用现代内固定方法与关节置换术的功能结果相似。然而,这些结果可能不适用于更年轻、更活跃的髋部骨折人群。证据等级:预后II级。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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