Feasibility and perioperative outcomes of re-operative retroperitoneal robotic partial nephrectomy.

IF 2.4 3区 医学 Q3 ONCOLOGY
Milan H Patel, Ruben Blachman-Braun, Lauren Loebach, Braden Millan, Jaskirat Saini, Sandeep Gurram, W Marston Linehan, Mark W Ball
{"title":"Feasibility and perioperative outcomes of re-operative retroperitoneal robotic partial nephrectomy.","authors":"Milan H Patel, Ruben Blachman-Braun, Lauren Loebach, Braden Millan, Jaskirat Saini, Sandeep Gurram, W Marston Linehan, Mark W Ball","doi":"10.1016/j.urolonc.2025.05.003","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To present our experience with re-operative retroperitoneal partial nephrectomy (Re-RetroPN), evaluate its feasibility and safety, and compare perioperative outcomes, including renal function metrics, pathology, and complication rates, between patients that underwent Re-RetroPN and those that underwent re-operative transperitoneal robotic partial nephrectomy (Re-TransPN).</p><p><strong>Methods: </strong>A retrospective cohort study was conducted identifying patients who underwent re-operative robotic partial nephrectomy (PN) at our institution from January 2008 to December 2024. Demographic, clinical, perioperative, and pathological data were recorded and analyzed.</p><p><strong>Results: </strong>A total of 186 patients who underwent robotic re-operative PN were analyzed (173 Re-TransPN vs. 13 Re-RetroPN), and 1 patient was converted from Re-RetroPN to Re-TransPN. Overall, 17 (9.1%) had a solitary kidney, 138 (74.2%) underwent their second ipsilateral partial nephrectomy, and 48 (25.8%) had their third. A total of 894 tumors were removed (825 with Re-TransPN, 69 with Re-RetroPN), with a median of 3 (2-6) tumors per procedure. Perioperative metrics, including estimated blood loss, operative time, and percentage of cases performed without hilar clamping were similar between groups. Positive surgical margins were observed in 7 (4.0%) patients in the Re-TransPN group, with no positive margins reported in the Re-RetroPN group. Renal function parameters at 3 months and complication rates were comparable between groups, with 1 (7.7%) patient in the Re-RetroPN group experiencing a Clavien-Dindo grade ≥3 complications.</p><p><strong>Conclusion: </strong>Re-RetroPN is a feasible and safe option for carefully selected patients, with comparable outcomes to Re-TransPN. It provides advantages in certain scenarios, such as improved access to posteriorly located tumors and avoidance of the peritoneal cavity.</p>","PeriodicalId":23408,"journal":{"name":"Urologic Oncology-seminars and Original Investigations","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urologic Oncology-seminars and Original Investigations","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.urolonc.2025.05.003","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: To present our experience with re-operative retroperitoneal partial nephrectomy (Re-RetroPN), evaluate its feasibility and safety, and compare perioperative outcomes, including renal function metrics, pathology, and complication rates, between patients that underwent Re-RetroPN and those that underwent re-operative transperitoneal robotic partial nephrectomy (Re-TransPN).

Methods: A retrospective cohort study was conducted identifying patients who underwent re-operative robotic partial nephrectomy (PN) at our institution from January 2008 to December 2024. Demographic, clinical, perioperative, and pathological data were recorded and analyzed.

Results: A total of 186 patients who underwent robotic re-operative PN were analyzed (173 Re-TransPN vs. 13 Re-RetroPN), and 1 patient was converted from Re-RetroPN to Re-TransPN. Overall, 17 (9.1%) had a solitary kidney, 138 (74.2%) underwent their second ipsilateral partial nephrectomy, and 48 (25.8%) had their third. A total of 894 tumors were removed (825 with Re-TransPN, 69 with Re-RetroPN), with a median of 3 (2-6) tumors per procedure. Perioperative metrics, including estimated blood loss, operative time, and percentage of cases performed without hilar clamping were similar between groups. Positive surgical margins were observed in 7 (4.0%) patients in the Re-TransPN group, with no positive margins reported in the Re-RetroPN group. Renal function parameters at 3 months and complication rates were comparable between groups, with 1 (7.7%) patient in the Re-RetroPN group experiencing a Clavien-Dindo grade ≥3 complications.

Conclusion: Re-RetroPN is a feasible and safe option for carefully selected patients, with comparable outcomes to Re-TransPN. It provides advantages in certain scenarios, such as improved access to posteriorly located tumors and avoidance of the peritoneal cavity.

腹膜后机器人肾部分切除术的可行性及围手术期疗效。
目的:介绍再手术腹膜后肾部分切除术(Re-RetroPN)的经验,评估其可行性和安全性,并比较再手术腹膜后机器人肾部分切除术(Re-TransPN)和再手术腹膜后机器人肾部分切除术(Re-TransPN)患者的围手术期预后,包括肾功能指标、病理和并发症发生率。方法:对2008年1月至2024年12月在我院再次行机器人肾部分切除术(PN)的患者进行回顾性队列研究。记录和分析人口统计学、临床、围手术期和病理资料。结果:共分析了186例接受机器人再手术PN的患者(173例Re-TransPN vs. 13例Re-RetroPN), 1例患者从Re-RetroPN转为Re-TransPN。总的来说,17例(9.1%)有一个肾,138例(74.2%)接受了第二次同侧部分肾切除术,48例(25.8%)接受了第三次肾切除术。共有894个肿瘤被切除(Re-TransPN 825个,Re-RetroPN 69个),每次手术中位数为3(2-6)个肿瘤。围手术期指标,包括估计的出血量、手术时间和不夹持门的病例百分比在两组之间相似。Re-TransPN组有7例(4.0%)患者的手术切缘呈阳性,Re-RetroPN组无阳性切缘报告。3个月时的肾功能参数和并发症发生率在两组之间具有可比性,Re-RetroPN组有1例(7.7%)患者出现Clavien-Dindo级≥3级并发症。结论:对于精心挑选的患者,Re-RetroPN是一种可行且安全的选择,其结果与Re-TransPN相当。它在某些情况下提供了优势,例如改善了进入后位肿瘤和避免腹腔。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
4.80
自引率
3.70%
发文量
297
审稿时长
7.6 weeks
期刊介绍: Urologic Oncology: Seminars and Original Investigations is the official journal of the Society of Urologic Oncology. The journal publishes practical, timely, and relevant clinical and basic science research articles which address any aspect of urologic oncology. Each issue comprises original research, news and topics, survey articles providing short commentaries on other important articles in the urologic oncology literature, and reviews including an in-depth Seminar examining a specific clinical dilemma. The journal periodically publishes supplement issues devoted to areas of current interest to the urologic oncology community. Articles published are of interest to researchers and the clinicians involved in the practice of urologic oncology including urologists, oncologists, and radiologists.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信