Management of early-onset scoliosis: modern Luque trolley technique led to fewer reoperations within 3 years than other growth-friendly techniques, a prospective cohort study with matched historical controls.
Romain Dayer, Michael Grevitt, Lee Breakwell, WaiWeng Yoon, Maio Chen, Tiara Ratz, Tina Szocik, Yaner Y Zhu, Jean Ouellet
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引用次数: 0
Abstract
Purpose: Management of early-onset scoliosis (EOS) remains challenging with high reoperation rates. The modern Luque trolley technique (MLT) was developed to reduce open lengthening and complications. This study aimed to compare the reoperation rates between the MLT and other growth-friendly surgical techniques.
Methods: Prospective EOS patients were recruited and treated with MLT; matched historical controls were selected from the Pediatric Spine Study Group (PSSG) database. The primary objective was to test if within 3 years of surgery MLT patients would have fewer reoperations. Secondary outcomes were growth, curve correction, and quality of life using the 24-item early-onset scoliosis questionnaire (EOSQ-24). Safety analysis was performed for the MLT patients.
Results: MLT (N = 18) and control patients (N = 43) had similar baseline age, body measurements, etiology, Cobb angle, and spinal length. Within 3 years of surgery, 1/18 MLT patients required a reoperation compared with 30/43 controls, conditional Poisson regression rate ratio = 0.02 (95% CI 0; 0.12) (P < 0.001). The median time to first reoperation was MLT, 5.4 years and control, 0.8 years. The MLT achieved the same curve correction as the controls at 3 years. The total spinal growth (T1-S1) was similar between the groups, although the thoracic spinal growth (T1-T12) was less in the MLT group. No difference was observed in standing heights and EOSQ-24 scores. Within 3 years, 2 MLT patients had recurrence of deformity (risk = 11.1%, 95% CI 1.4; 34.7) and 1 had implant loosening (risk = 5.6%, 95% CI 0.1; 27.3).
Conclusion: MLT patients had fewer reoperations within 3 years than control patients and a low risk of implant failure.
Levels of evidence: Level II.
Trial registration number: NCT01672749. Date of registration: 2012-08-24.
期刊介绍：
Spine Deformity the official journal of the?Scoliosis Research Society is a peer-refereed publication to disseminate knowledge on basic science and clinical research into the?etiology?biomechanics?treatment?methods and outcomes of all types of?spinal deformities. The international members of the Editorial Board provide a worldwide perspective for the journal's area of interest.The?journal?will enhance the mission of the Society which is to foster the optimal care of all patients with?spine?deformities worldwide. Articles published in?Spine Deformity?are Medline indexed in PubMed.? The journal publishes original articles in the form of clinical and basic research. Spine Deformity will only publish studies that have institutional review board (IRB) or similar ethics committee approval for human and animal studies and have strictly observed these guidelines. The minimum follow-up period for follow-up clinical studies is 24 months.
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