A multidisciplinary meeting for generating a personalized pharmaceutical plan for older adults at hospital discharge: the IATROPREV study.

IF 3.1 3区 医学 Q2 PHARMACOLOGY & PHARMACY
Chloé Cornille, Aurélie Lenglet, Bertrand Decaudin, François Puisieux, Lisa Mondet, Anne Toulemonde, Sophie Gautier, Grégory Tempremant, Jean-Paul Kornobis, Mathilde Dambrine, Thomas Renoncourt, Frédéric Bloch, Jean-Baptiste Beuscart
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Abstract

Aims: The French government's IATROPREV program has been designed to assess the effectiveness and safety of medications prescribed to older adults discharged from acute geriatric units. IATROPREV includes the implementation of a personalized pharmaceutical plan validated at a multidisciplinary meeting attended by the patient's geriatrician, family physician, community pharmacist and hospital pharmacist. We hypothesized that a multidisciplinary meeting on discharge from hospital will enable the recommendations to be largely followed up.

Methods: A prospective, observational, multicentre study was conducted to analyse the personalized pharmaceutical plan and follow-up at 45 and 90 days for patients discharged from an acute geriatric unit between February 2021 and August 2023.

Results: Of 708 eligible patients, 380 (54%) were included. The main reason for non-inclusion was the family physician's refusal to participate. A total of 5977 recommendations (i.e., an average of 15 per patient) were issued during the multidisciplinary meeting. Seventy percent of these recommendations concerned medication adjustments. The remaining recommendations were related to clinical and laboratory follow-up, the management of home care, and vaccination updates. Follow-up data at 90 days were available for 295 (78%) of the 380 patients. At 90 days, the recommendation implementation rate was 83% (4178 out of 5977) overall, 86% for medication adjustments, 79% for patient monitoring, 87% for home care management and 56% for vaccinations.

Conclusions: IATROPREV is designed for patients with major therapeutic complexity. It enables a significant number of treatment optimization recommendations to be implemented within 90 days, thanks in particular to the multidisciplinary meeting.

为老年人在出院时制定个性化药物计划的多学科会议:IATROPREV研究。
目的:法国政府的IATROPREV项目旨在评估从急性老年病房出院的老年人处方药物的有效性和安全性。IATROPREV包括实施一项个性化用药计划,该计划在由患者的老年病专家、家庭医生、社区药剂师和医院药剂师参加的多学科会议上得到验证。我们假设,在出院时召开多学科会议将使这些建议在很大程度上得到跟进。方法:采用前瞻性、观察性、多中心研究,分析2021年2月至2023年8月间某急性老年病房出院患者的个性化用药方案及45天和90天随访情况。结果:在708例符合条件的患者中,纳入380例(54%)。未纳入的主要原因是家庭医生拒绝参与。在多学科会议期间共发布了5977条建议(即平均每位患者15条建议)。其中70%的建议涉及药物调整。其余建议与临床和实验室随访、家庭护理管理和疫苗接种更新有关。380例患者中有295例(78%)可获得90天的随访数据。在第90天,建议执行率为83%(5977人中有4178人),药物调整率为86%,患者监测率为79%,家庭护理管理率为87%,疫苗接种率为56%。结论:IATROPREV专为具有重大治疗复杂性的患者设计。它使大量的治疗优化建议能够在90天内实施,特别是多学科会议。
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来源期刊
CiteScore
6.30
自引率
8.80%
发文量
419
审稿时长
1 months
期刊介绍: Published on behalf of the British Pharmacological Society, the British Journal of Clinical Pharmacology features papers and reports on all aspects of drug action in humans: review articles, mini review articles, original papers, commentaries, editorials and letters. The Journal enjoys a wide readership, bridging the gap between the medical profession, clinical research and the pharmaceutical industry. It also publishes research on new methods, new drugs and new approaches to treatment. The Journal is recognised as one of the leading publications in its field. It is online only, publishes open access research through its OnlineOpen programme and is published monthly.
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