Challenges implementing technology transfer as a viable pathway for equitable vaccine production and access: A case study of the mRNA vaccine hub in South Africa.

IF 2.1 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Global Public Health Pub Date : 2025-12-01 Epub Date: 2025-05-27 DOI:10.1080/17441692.2025.2504698
Omowamiwa Kolawole, Caroline Ncube, Jeremy de Beer
{"title":"Challenges implementing technology transfer as a viable pathway for equitable vaccine production and access: A case study of the mRNA vaccine hub in South Africa.","authors":"Omowamiwa Kolawole, Caroline Ncube, Jeremy de Beer","doi":"10.1080/17441692.2025.2504698","DOIUrl":null,"url":null,"abstract":"<p><p>In the face of the COVID-19 pandemic, there have been renewed calls for more equitable vaccine access. These calls have in turn resulted in interventions to increase vaccine manufacturing capacity as one of the key interventions to address global vaccine access. However, skill gaps in manufacturing capacity point out the critical need for technology transfer and more open science. The World Health Organization-instituted mRNA hub in South Africa has been positioned as an initiative to facilitate technology transfer for building and leveraging vaccine manufacturing capacity in low and middle income countries. Our case study examines the activities of the mRNA vaccine hub, highlighting challenges that can stifle the long-term goals of equitable vaccine production if left unaddressed. The findings suggest that for technology transfer to be effective, there must be sufficient institutional commitment, adequate funding that is fit for purpose, clear terms and an enabling legal and socio-economic environment.</p>","PeriodicalId":12735,"journal":{"name":"Global Public Health","volume":"20 1","pages":"2504698"},"PeriodicalIF":2.1000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global Public Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/17441692.2025.2504698","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/27 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0

Abstract

In the face of the COVID-19 pandemic, there have been renewed calls for more equitable vaccine access. These calls have in turn resulted in interventions to increase vaccine manufacturing capacity as one of the key interventions to address global vaccine access. However, skill gaps in manufacturing capacity point out the critical need for technology transfer and more open science. The World Health Organization-instituted mRNA hub in South Africa has been positioned as an initiative to facilitate technology transfer for building and leveraging vaccine manufacturing capacity in low and middle income countries. Our case study examines the activities of the mRNA vaccine hub, highlighting challenges that can stifle the long-term goals of equitable vaccine production if left unaddressed. The findings suggest that for technology transfer to be effective, there must be sufficient institutional commitment, adequate funding that is fit for purpose, clear terms and an enabling legal and socio-economic environment.

将技术转让作为公平疫苗生产和获取的可行途径实施的挑战:对南非mRNA疫苗中心的案例研究。
面对COVID-19大流行,人们再次呼吁更公平地获得疫苗。这些呼吁反过来产生了提高疫苗生产能力的干预措施,作为解决全球疫苗获取问题的关键干预措施之一。然而,制造能力方面的技能差距指出了技术转让和更开放的科学的迫切需要。世界卫生组织在南非设立的信使rna中心被定位为一项倡议,旨在促进技术转让,以便在低收入和中等收入国家建立和利用疫苗制造能力。我们的案例研究考察了mRNA疫苗中心的活动,强调了如果不加以解决,可能会阻碍公平疫苗生产长期目标的挑战。调查结果表明,要使技术转让有效,必须有充分的机构承诺、适合目的的充足资金、明确的条款和有利的法律和社会经济环境。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Global Public Health
Global Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
6.50
自引率
3.00%
发文量
120
期刊介绍: Global Public Health is an essential peer-reviewed journal that energetically engages with key public health issues that have come to the fore in the global environment — mounting inequalities between rich and poor; the globalization of trade; new patterns of travel and migration; epidemics of newly-emerging and re-emerging infectious diseases; the HIV/AIDS pandemic; the increase in chronic illnesses; escalating pressure on public health infrastructures around the world; and the growing range and scale of conflict situations, terrorist threats, environmental pressures, natural and human-made disasters.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信