A two-phase approach to identifying HFpEF in heart failure patients: Risk score evaluation and decision tree development.

IF 3.2 2区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Izabella Uchmanowicz, Magdalena Lisiak, Piotr Ponikowski, Ewa A Jankowska, Andrzej Mysiak, Marta Wleklik
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引用次数: 0

Abstract

Aims: Heart failure (HF) with preserved ejection fraction (HFpEF) poses significant diagnostic challenges due to its complex aetiology and overlapping symptoms with other HF types. The heterogeneity of HFpEF, compounded by frequent comorbidities, complicates diagnosis. This study aimed to enhance HFpEF prediction through a two-phase approach: a simplified risk score and a decision tree model.

Methods and results: In Phase 1, an 8-point risk score based on accessible clinical parameters was developed. In Phase 2, we conducted comprehensive predictive modelling using decision tree analysis. Data from 560 HF patients were analysed. It achieved an accuracy of 63.13% (sensitivity: 62.87%, specificity: 54.24%). In Phase 2, a decision tree model using broader clinical variables improved accuracy to 73.04% (sensitivity: 53.89%, specificity: 81.17%).

Conclusions: This dual framework provides tools for both quick screening and detailed risk stratification in various clinical settings.

确定心力衰竭患者HFpEF的两阶段方法:风险评分评估和决策树的制定。
目的:保留射血分数(HFpEF)心力衰竭(HF)由于其复杂的病因和与其他HF类型重叠的症状,给诊断带来了重大挑战。HFpEF的异质性,加上常见的合并症,使诊断复杂化。本研究旨在通过简化风险评分和决策树模型两阶段方法来增强HFpEF的预测。方法和结果:在第一阶段,基于可获得的临床参数制定了8分风险评分。在第二阶段,我们使用决策树分析进行了全面的预测建模。分析了560例心衰患者的数据。准确度为63.13%,灵敏度为62.87%,特异度为54.24%。在第二阶段,使用更广泛的临床变量的决策树模型将准确率提高到73.04%(敏感性:53.89%,特异性:81.17%)。结论:这一双重框架为各种临床环境中的快速筛查和详细的风险分层提供了工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ESC Heart Failure
ESC Heart Failure Medicine-Cardiology and Cardiovascular Medicine
CiteScore
7.00
自引率
7.90%
发文量
461
审稿时长
12 weeks
期刊介绍: ESC Heart Failure is the open access journal of the Heart Failure Association of the European Society of Cardiology dedicated to the advancement of knowledge in the field of heart failure. The journal aims to improve the understanding, prevention, investigation and treatment of heart failure. Molecular and cellular biology, pathology, physiology, electrophysiology, pharmacology, as well as the clinical, social and population sciences all form part of the discipline that is heart failure. Accordingly, submission of manuscripts on basic, translational, clinical and population sciences is invited. Original contributions on nursing, care of the elderly, primary care, health economics and other specialist fields related to heart failure are also welcome, as are case reports that highlight interesting aspects of heart failure care and treatment.
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