Familial giant cell arteritis.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL
Yi Ling Dai, Ali Khodor, Raul Ruiz-Lozano, Susan Tucker
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引用次数: 0

Abstract

The genetic basis of giant cell arteritis is not fully understood but may play a role in treatment resistance and increased risk of ischaemic complications, including permanent vision loss. We present two of five cases of familial giant cell arteritis (2.5%) among 198 temporal artery biopsy-positive patients seen at a single institution over a 20-year period between 2003 and 2023 to highlight the importance of further genetic studies in this group of patients to improve timely diagnosis, management and detection of patients at greatest risk for ischaemic sequelae.

家族性巨细胞动脉炎。
巨细胞动脉炎的遗传基础尚不完全清楚,但可能在治疗抵抗和缺血性并发症风险增加(包括永久性视力丧失)中发挥作用。在2003年至2023年的20年间,我们报告了198例颞动脉活检阳性患者中5例家族性巨细胞动脉炎中的2例(2.5%),以强调进一步的遗传学研究对这组患者的重要性,以提高对缺血性后遗症高风险患者的及时诊断、管理和检测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMJ Case Reports
BMJ Case Reports Medicine-Medicine (all)
CiteScore
1.40
自引率
0.00%
发文量
1588
期刊介绍: BMJ Case Reports is an important educational resource offering a high volume of cases in all disciplines so that healthcare professionals, researchers and others can easily find clinically important information on common and rare conditions. All articles are peer reviewed and copy edited before publication. BMJ Case Reports is not an edition or supplement of the BMJ.
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